Large study links poor vitamin D status with greater risk of dying over 8 year period

Readers of Life Extension Update will recall the June 24, 2008 issue which reported the finding of Austrian and German researchers that men and women with higher serum levels of vitamin D had a reduced risk of dying from all causes over a seven year period.

The study, which included 3,258 patients scheduled for coronary angiography, was reported in the June 23, 2008 issue of the American Medical Association journal Archives of Internal Medicine. Now, in the August 11/25, 2008 issue of the journal, researchers in the U.S. report the results of a significantly larger study involving healthy men and women which found a similar association. The study is the first, to the authors’ knowledge, to examine the association between vitamin D levels and mortality in the general population.

For the current study, Michal L. Melamed, MD, MHS, of the Bronx’s Albert Einstein College of Medicine, along with researchers from Johns Hopkins University evaluated data from 13,331 participants in the Third National Health and Nutritional Examination Survey (NHANES III). Serum 25-hdyroxyvitamin D levels were measured between 1988 and 1994, and subjects were followed through 2000.Over the 8.7 year median follow-up period, 1,806 deaths occurred, including 777 from cardiovascular disease, 424 from cancer, and 105 due to infectious causes.



Participants with the lowest serum vitamin D levels were found to have the greatest risk of dying from any cause over follow-up. Among those whose levels placed them among the lowest 25 percent of participants at less than 17.8 nanograms per liter, there was a 26 percent higher risk of dying compared with those whose levels were in the top 25 percent. Continue Reading

Orthomolecular Medicine - For Health and Mental Illness

Orthomolecular medicine describes the practice of preventing and treating disease by providing the body with optimal amounts of substances which are natural to the body. The term "orthomolecular" was first used by Linus Pauling in a paper he wrote in the journal Science in 1968. This paper first described the theoretical foundations for what was later to become a specialty within complementary medicine.

The key idea in orthomolecular medicine is that genetic factors are central not only to the physical characteristics of individuals, but also to their biochemical milieu. Biochemical pathways of the body have significant genetic variability in terms of transcriptional potential and individual enzyme concentrations, receptor-ligand affinities and protein transporter efficiency. Diseases such as atherosclerosis, cancer, schizophrenia or depression are associated with specific biochemical abnormalities which are either causal or aggravating factors of the illness. In the orthomolecular view, it is possible that the provision of vitamins, amino acids, trace elements or fatty acids in amounts sufficient to correct biochemical abnormalities will be therapeutic in preventing or treating such diseases.Want to learn more? The following essays give a more detailed overview of the nature, efficacy and history of orthomolecular medicine. Continue Reading >>

Are RDA Nutrient Levels Safe?

RDAs or Recommended Dietary Allowances of vital nutrients such as vitamins and minerals and minerals, are being promoted by health authorities as the level of consumption at which we may feel comfortable about having "taken care of our needs" - but is that really the truth?

Developed during the wartime 40s, the purpose was to identify a diet that would allow US soldiers to fight as well as those staying home to survive without getting sick from malnourishment. After the war, dietary allowances became a part of standard health practice in many western countries. Note that there was no intention to assure optimum health, merely the absence of those deficiency diseases that had been identified at the time. Although refinements have taken place over the years, the basic philosophy of RDAs has remained the one implicit in the original purpose. Continue Reading >>

Reduced serum vitamin E predicts physical decline in older individuals

The January 23, 2008 issue of the Journal of the American Medical Association published the finding of Benedetta Bartali, RD, PhD, of Yale University School of Medicine and colleagues that having reduced serum levels of vitamin E, an indicator of poor nutrition, is significantly associated with a decline in physical function among men and women aged 65 and older.

The current study included 698 participants in the Invecchiare in Chianti (InCHIANTI) study of risk factors contributing to physical function decline among aging men and women living in Tuscany, Italy. Examinations of the participants were performed upon enrollment from November, 1998 through May, 2000 and tests of physical function, including walking speed, chair rises, and standing balance, were conducted. Fasting blood samples were evaluated for serum concentrations of folate, vitamins B6, B12, D, E (alpha-tocopherol), and iron. Reassessment of physical function occurred at three-year follow-up examinations which took place between 2001 and 2003. Continue Reading

Linus Pauling--Molecular Diseases, Sickle Cell Anemia

Sickle cell anemia is a serious condition in which the red blood cells can become sickle-shaped (that is, shaped like a "C").

Normal red blood cells are smooth and round like a doughnut without a hole. They move easily through blood vessels to carry oxygen to all parts of the body. Sickle-shaped cells don't move easily through blood. They're stiff and sticky and tend to form clumps and get stuck in blood vessels.

The clumps of sickle cells block blood flow in the blood vessels that lead to the limbs and organs. Blocked blood vessels can cause pain, serious infections, and organ damage. http://www.nhlbi.nih.gov/health/dci/Diseases/Sca/SCA_WhatIs.html

Clinical trial to test vitamin C against non-Hodgkin lymphoma

Researchers at Thomas Jefferson University Hospital and the Kimmel Cancer Center in Philadelphia, in collaboration with the National Institutes of Health, are initiating a trial to test the effects of high dose vitamin C in patients with non-Hodgkin's lymphoma (NHL). The study will be the first to test the effects of the vitamin when administered intravenously to NHL patients.

A team led by Daniel Monti, MD, who is the director of the Myrna Brind Center of Integrative Medicine at Thomas Jefferson, plans to enroll twenty patients for whom standard non-Hodgkin lymphoma therapy has been unsuccessful. Trial participants will receive varying doses of intravenous vitamin C three times per week while being monitored for disease progression. Continue Reading

Some genetic defects treatable with supplements

An article published early online on June 3, 2008 in the Proceedings of the National Academy of Sciences reports the prediction of Jasper Rine and colleagues at the University of California, Berkeley that soon-to-be-available personalized genome sequencing will uncover minor genetic flaws that can easily be corrected with nutrition, enabling people to personalize their supplement routine.

"Headlines for the last 20 years have really been about the triumph of biomedical research in finding disease genes, which is biologically interesting, genetically important and frightening to people who get this information," Dr Rine. "I became obsessed with trying to decide if there is some other class of information that will make people want to look at their genome sequence."Variations in genes responsible for the production of enzymes involved in metabolism affect the efficiency of these enzymes.

While having two copies of a defective gene can result in one of many rare metabolic diseases that can be treated with vitamin supplements, many individuals have only one copy, or have two copies of only slightly defective genes, whose subtle effects on enzymes, Dr Rine’s team found, could also be remedied by vitamin supplementation. The current study examined one human enzyme, methylenetetrahydrofolate reductase (MTHFR), which requires the B vitamin folate to function properly.

The enzyme plays a role in DNA nucleotide synthesis. Among 564 individuals, 3 common variants and 11 minor, uncommon genetic variants of MTHFR were found. When these gene variants were synthesized and inserted into yeast cells, the most common variant and 4 of the uncommon variants were found to affect the enzyme's function, yet supplementation of the yeast with folate restored full functionality to all but one of these. Continue Reading

When Oxidants Can Increase Risk of Death

1. When Antioxidants Can Increase Risk of DeathThe truth about these nutrients - their benefits and risks

Antioxidants have long been considered good news, helping to reduce the 'oxidative' damage caused by everyday living that ages and eventually kills us. We are encouraged to eat foods (especially our 'five a day') that provide rich sources of antioxidant nutrients, and a massive market for antioxidant supplements has sprung up with literally thousands of studies to affirm their benefits.

But in the last few years, a number of big trials have apparently shown that taking extra antioxidants in the form of supplements doesn't work. They have reported that antioxidants, far from staving off the big killers such as cancer and heart disease, can actually make them worse. A recent review of a number of studies gave rise to media headlines such as "Antioxidants can kill".

So what is going on?
After numerous studies that showed extra antioxidants reduced risk of disease, some more recent research started to look at their effect on two particular 'at-risk' groups - people who smoked and those with cardiovascular disease.

Several of these trials showed that the risk of cancer in smokers increased slightly when they were given beta-carotene. Other studies suggested a small increased risk of heart attack in heart patients who were on medications such as statins and taking vitamin E.
What's interesting to note, however, is that far from putting the nail in the coffin of antioxidants, these studies give us an interesting insight into how these nutrients work - and why people who smoke or take statins are at risk, unless they adapt (rather than stop) their supplement intake.
For example, the recent Cochrane Review by Bjelakovic et al actually found that people who took BOTH multivitamin AND antioxidant supplements showed no increased risk, and in some cases, a significant decrease in risk. Now why should that be, and what does it tell us about the way antioxidants work?

I believe it points to a simple explanation as to why high-dose vitamin E increases cardiovascular risk, why beta-carotene increases smokers' risk, and why multivitamins eradicate this risk.
With this month's 100%health newsletter, I have produced a Special Report which looks in detail as these issues.

Find out:
. Why statins make high-dose vitamin E dangerous
. The nutrients that can reduce disease risk for smokers
. Why the Cochrane review is flawed
. The reactions to the review's findings from scientists whose studies were included
. The positive findings that went unreported
. And most importantly, what you can do to protect yourself - whether you're taking statins or smoking, are elderly or young, in good health or bad.

Click here to make sure you receive your copy.
My July newsletter also tackles the controversial issue of Childhood Vaccinations and looks at the evidence behind the guidelines so many parents are questioning.
I'll also be exploring the latest research into anti-ageing to bring you the best tips to help you turn the clock back and stay youthful.

And there's another Special Report on the plant compounds Salvestrols - a new discovery that could provide a major breakthrough in the prevention and treatment of cancer.
To ensure you receive all this - plus a whole range of exclusive member benefits - click here to join 100%health.

2. Two days is all it takes to change your life. Book now to qualify for Early Bird discounts
Learn how to build up your energy, control your weight and beat nagging problems that plague your health.

Our ever popular 100%health Weekend Workshop will give you manageable tools to combat the obstacles in your life that are holding you back. All you need is the desire and determination to transform your life. We do the rest by tailor-making a new life plan for you.

The next workshop is on 27th/28th September in London and I will spend two days taking you through a step-by-step guide to the eight key areas that will lead you to optimum health including information on the best foods to eat, why eating low-GL is best, cookery demonstrations and a personalised Health Action Plan. Plus a follow-up online health assessment to help you track your progress.

What you'll achieve
By the end of the weekend you will know exactly what you need to do to achieve the boundless energy, sharp mind, balanced mood, stable weight and glowing skin that are the hallmark of great health. We give you the tools to do it and the confidence to follow it through.
Book today and take the first step. I very much hope you will join me on the next 100%health Workshop in London on 27th/28th September. Places strictly limited - book your ticket now to qualify for the Early Bird discount of £50! Click here for more details and how to book.
Don't forget - if you're a member of 100%health you'll automatically save a further £30 on your booking - click here to join.

3. Are you interested in becoming a nutritional therapist?
The Institute for Optimum Nutrition offers a 3-year part time foundation science degree in nutritional therapy.

If you are interested in studying nutrition to qualify as a nutritional therapist , the Institute for Optimum Nutrition have asked me to let you know there are still some places available on their excellent course commencing this September. To find out more book your place on one of the remaining open days see the ION website for more details: http://www.ion.ac.uk/open_days.htm
Wishing you the best of health,
Patrick Holford

Breast cancer

The following supplementation regimen is suggested. As always, consult your physician before beginning any nutritional supplementation regimen.

Dual-Action Cruciferous Vegetable Extract With Cat's Claw, 1-2 capsules per day.

Lightly caffeinated green tea extract, three 725 mg capsules, two times a day with meals. Use decaffeinated green tea extract if you are sensitive to caffeine or want to use the less-stimulating version with the evening dosage.
CLA or CLA with Guarana, 3000 to 4000 mg daily of CLA and about 300 mg of guarana, early in the day.

Melatonin, 3 to 50 mg at bedtime.
PhytoFood Powder (broccoli, cabbage, and other cruciferous vegetables that provide sulphoraphane and other cancer-fighting plant extracts), 1-2 tbsp daily.
Se-methylselenocysteine, 200 to 400 mcg daily.
CoQ10, three 100 mg softgels in divided doses. Note the caution stated in this protocol.
Super EPA/DHA w/Sesame Lignans, 8 softgels daily, in divided doses. Take with nonfiber meals.
Vitamin D3, 4000 to 6000 IU taken daily with monthly blood testing to monitor for toxicity. Reduce dosage at 6 months.
Water-soluble vitamin A, 100,000 to 300,000 IU daily with monthly blood testing to monitor for toxicity. Reduce dosage at 6 months (refer to vitamin A precautions in Appendix A). Continue Reading

DEPRESSION, MENTAL ILLNESS CURED WITH NUTRITION

Orthomolecular Medicine News Service, October 7, 2005

Mental Health Treatment That Works
(OMNS) Doctors report that mental health problems including depression, bipolar disorder, schizophrenia, ADHD, anti-social and learning disorders, and obsessive-compulsive disorders often have a common cause: insufficient nutrients in the brain. Nutritionally-oriented physicians assert that the cure for these problems is to give the body the extra nutrients it needs, especially when under abnormal stress.

Orthomolecular medical researchers say the future of psychiatry is in nutrition because nutrition has such a long, safe and effective history of correcting many mental problems. Nutrients such as the B-vitamins are most successful when taken regularly, taken in relatively high doses, and taken in conjunction with vitamin C, the essential fatty acids (EFA’s), and the minerals magnesium and selenium.

A summary of what has worked for many people follows below. The safety of vitamins and minerals is extraordinary, and the expense of trying them is much less than the cost of hazardous pharmaceutical drugs. These nutrients can be purchased in a discount or heath store.

Taking 1,000 mg of vitamin B-3 three times a day often cures mild to moderate depression. Dramatic results are often achieved within one week of beginning this nutritional program, especially in alcoholics. (1)

Sometimes a simple deficiency of vitamin D causes depression. 3,000 I.U./day from all sources can alleviate the problem. (2)

3,000 mg/day or more of niacin (vitamin B-3), along with the same quantity of vitamin C, taken in divided doses throughout the day can successfully treat both schizophrenia and bipolar disorder. (3)

Vitamins B-3, B-6, C and the minerals magnesium and zinc frequently produce a good response in ADHD and autistic children. (4)

Vitamins B-6, folate, and B-12 taken together lower elevated homocysteine levels in the elderly while improving mental function. (5)

As pointed out by chemistry professor and vitamin discoverer Roger J. Williams, PhD (6), each individual has different nutritional needs and responds differently to nutrients. Are you tired of being depressed, suffering from anxiety, paying huge prescription drug bills for unsafe prescriptions that don’t solve the problem or produce undesirable side effects? Are you tired of the piece-meal trial and error approach to finding a solution to your mental or emotional problems? If so, adults should consider the following nutritional protocol, which will bathe your brain and nerves in natural nutrients and may well produce dramatic results. The cost of trying the program below is less than the cost of a typical doctor’s office visit. It is safe and convenient. All of these nutrients can be purchased at large discount stores. Continue reading >>

Niacin (Vitamin B3) Lowers High Cholesterol Safely

OMNS - There is a safe, inexpensive, nonprescription, convenient and effective way to reduce high cholesterol levels and reduce heart disease risk: niacin. Niacin is a water-soluble B-complex vitamin, vitamin B-3. One of niacin's unique properties is its ability to help you naturally relax and to fall asleep more rapidly at night. It is well established that niacin helps reduce harmful cholesterol levels in the bloodstream. Niacin is one of the best substances for elevating high density lipoprotein cholesterol (the "good cholesterol) and so decreases the ratio of the total cholesterol over high density cholesterol.

The finding that niacin lowered cholesterol was soon confirmed by Parsons, Achor, Berge, McKenzie and Barker (1956) and Parsons (1961, 1961a, 1962) at the Mayo Clinic, which launched niacin on its way as a hypocholesterolemic substance. Since then it has been found to be a normalizing agent, meaning it elevates high density lipoprotein cholesterol, decreases low density and very low density lipoprotein cholesterol and lowers triglycerides. Grundy, Mok, Zechs and Berman (1981) found it lowered cholesterol by 22 percent and triglycerides by 52 percent and wrote, "To our knowledge, no other single agent has such potential for lowering both cholesterol and triglycerides."

Elevated cholesterol levels are associated with increased risk of developing coronary disease. In addition to niacin, a typical diet generally recommended by orthomolecular physicians will tend to keep cholesterol levels down in most people. This diet can be described as a high fiber, sugar-free diet which is rich in complex polysaccharides such as vegetables and whole grains.

With adequately high doses of niacin, it is possible to lower cholesterol levels even with no alteration in diet. E. Boyle, then working with the National Institutes of Health in Washington, D.C., quickly became interested in niacin. He began to follow a series of patients using 3 grams (3,000 milligrams) of niacin per day. He reported his conclusions in a document prepared for physicians involved in Alcoholics Anonymous by Bill W (1968). In this report, Boyle reported that he had kept 160 coronary patients on niacin for ten years. Only six died, against a statistical expectation that 62 would have died with conventional care. He stated, "From the strictly medical viewpoint I believe all patients taking niacin would survive longer and enjoy life much more." His prediction came true when the National Coronary Drug Study was evaluated by Canner recently. But Boyle's data spoke for itself. Continuous use of niacin will decrease mortality and prolong life. Continue reading >>

VITAMIN C KILLS CANCER CELLS

Intravenous Vitamin C is Selectively Toxic to Cancer Cells
(OMNS) National Institutes of Health scientists have confirmed the concepts that vitamin C is selectively toxic to cancer cells and that tumor-toxic levels of vitamin C can be attained using intravenous administration. The article, published in the September 12, 2005 issue of the Proceedings of the National Academy of Sciences (1) concluded, “These findings give plausibility to intravenous ascorbic acid in cancer treatment.”

Orthomolecular medical researchers, including Nobel laureate Linus Pauling, have long recognized the great importance of vitamin C in fighting cancer. (2) Scientists associated with the Bio-Communications Research Institute (BRCI) in Wichita, Kansas have published 20 scientific articles on the subject. (3) BCRI researchers first reported in 1995 that vitamin C in sufficient amounts is selectively toxic to tumor cells. The authors concluded that tumor-toxic levels of vitamin C could be achieved only by giving the vitamin intravenously. Subsequent research from BCRI, published in the British Journal of Cancer in 2001 (4), was the first to describe in detail the pharmacokinetics of high doses of intravenous vitamin C.

"It is gratifying to have our research on vitamin C and cancer confirmed by scientists at the prestigious National Institutes of Health," said Neil Riordan, Ph.D., BCRI’s Research Director. “The findings reinforce our goal and commitment to pursue cutting edge cancer research,” added Michael Gonzalez, Ph.D., D.Sc. of the University of Puerto Rico.

BCRI’s vitamin C research was headed by its founder Hugh D. Riordan, M.D. The research team includes Dr. Xiaolong Meng, Dr. Joseph Casciari, Dr. Nina Mikirova, Dr. Jie Zhong, Dr. James A. Jackson, Dr. Don Davis, Dr. Jorge Miranda, Dr. Michael Gonzalez, Dr. Neil Riordan, and Mr. Paul Taylor.

What is Orthomolecular Medicine?
Linus Pauling defined orthomolecular medicine as "the treatment of disease by the provision of the optimum molecular environment, especially the optimum concentrations of substances normally present in the human body." Orthomolecular medicine uses safe, effective nutritional therapy to fight illness. For more information: http://www.orthomolecular.org/

Continue reading >>

HIGH-DOSE VITAMIN C FIGHTS ASTHMA

(OMNS) People with severe asthma have low blood concentrations of ascorbate (vitamin C), particularly men [1] and children [2].

Effective asthma treatment is readily available with cheap, safe and convenient vitamin C. The only requirement is to take enough vitamin C to be effective. Typical dietary quantities and low supplemental doses do not work. Robert F. Cathcart III, M.D., who has treated many asthma sufferers, says “Asthma is most often relieved by bowel tolerance doses of ascorbate (vitamin C). A child regularly having asthmatic attacks following exercise is usually relieved of these attacks by large doses of ascorbate. So far all of my patients having asthmatic attacks associated with the onset of viral diseases have been ameliorated by this treatment.”[3]

If you want asthma relief, consider trying this:

Go to a discount store and buy a large bottle of 1,000 mg vitamin C tablets. The cost should be less than $15.

Beginning when you awake in the morning, take 1,000 to 2,000 mg of vitamin C every 30 minutes and continue doing so until you have a single episode of loose stool (not quite diarrhea). If you haven’t had loose stool after 15 hours on this dosage, increase the vitamin C to 3000 mg every 30 minutes.

After you have a loose bowel movement, reduce the dosage to 2,000 mg of vitamin C every hour. You will quickly find the dosage that is right for you. Adjust the dosage of vitamin C downward to stay below the dosage that will cause loose stool and adjust it upward to relieve asthma symptoms. The usual maintenance dosage to remain asthma-free is 15,000 to 50,000 mg of vitamin C per day taken in eight equally divided doses.

People with asthma should also avoid tobacco smoke, minimize stress in their lives and minimize their consumption of junk foods, meat and dairy products.

Remember:
Vitamin C replaces antibiotics, antihistamines, antipyretics, antitoxics, and antiviral drugs at saturation (bowel tolerance) levels. It reduces inflammation.

A vitamin can act as a drug, but a drug can never act as a vitamin. Continue reading >>

VITAMIN C DOES NOT CAUSE KIDNEY STONES

By Steve Hickey, PhD and Hilary Roberts, PhD.

(OMNS) It is strange how some medical authors seem desperate to show that vitamin C causes harm. One recurrent scare story is that vitamin C might cause kidney stones. However, although such warnings pop up regularly, these reports do not demonstrate an increase in the number or size of stones; instead, they rely on vague indicators of improbable risk.

The authors of such uncritical papers have probably not read the literature, for this is an old story. Decades ago, the idea that vitamin C causes kidney stones formed part of the medical attack on Linus Pauling. While it was initially a reasonable hypothesis, unexpected kidney stones are not found in people taking large amounts of vitamin C. (1,2)

There is no evidence that vitamin C causes kidney stones. Indeed, in some cases, high doses may be curative. (3) A recent, large-scale, prospective study followed 85,557 women for 14 years and found no evidence that vitamin C causes kidney stones. (4) There was no difference in the occurrence of stones between people taking less than 250 milligrams per day and those taking 1.5 grams or more. This study was a follow up of an earlier study on 45,251 men. This earlier study indicated that doses of vitamin C above 1.5 grams reduce the risk of kidney stones. (5) The authors of these large studies stated that restriction of higher doses of vitamin C because of the possibility of kidney stones is unwarranted.

People with recurrent stone formation may have an unusual biochemistry, leading to increased production of oxalate from vitamin C. (6) Oxalate and urate can accumulate in kidney stones. In practice, there is an increased excretion of both oxalate and urate with gram level doses of vitamin C (ascorbate). Various authors over the years have used this increase to predict that vitamin C will cause kidney stones; however, these predictions have never been confirmed.

Around three quarters of all kidney stones are composed of calcium oxalate; unlike some other stone types, these can form in acidic urine. Although vitamin C does increase the production of oxalate in the body, there is no evidence that it increases stone formation. It could even have the reverse effect, for several reasons. Firstly, vitamin C tends to bind calcium, which could decrease its availability for formation of calcium oxalate. Secondly, vitamin C has a diuretic action: it increases urine flow, providing an environment that is less suitable for formation of kidney stones. Finally, stone formation appears to occur around a nucleus of infection. High concentrations of vitamin C are bactericidal and might prevent stone formation by removing the bacteria around which stones form.

Vitamin C could also prevent other types of kidney stones. Less common forms of stone include uric acid stones (8%), that form in gout, and cystine stones (1%), which can occasionally be formed in children with a hereditary condition; these stones are not side effects of vitamin C. Other stones include those made from calcium phosphate (5%), which dissolve in a vitamin C solution. Acid urine, produced by ascorbate, will also dissolve the struvite stones (magnesium ammonium phosphate) that often occur in infected urine.

Recently, Linda Massey and colleagues from Washington State University have claimed that vitamin C increases the risk of kidney stones. (7) Their paper illustrates how the claims of risk have little basis in fact. Massey claims that vitamin C supplementation can increase the amount of oxalate. Vitamin C can increase oxalate absorption and, if degraded in the body, ascorbate can be converted into oxalate. However, while oxalate is a constituent of some types of kidney stone, an increase in its concentration does not mean that more or larger kidney stones will be formed. The formation of kidney stones is influenced by many factors and, as we have seen, vitamin C might be predicted to inhibit several aspects of stone generation. Massey suggests that this increase in oxalate may increase the risk of stones. This is a weak suggestion, which is contradicted by substantial evidence, quoted above. Continue reading >>

Doctors Report Vitamin C Cures Shingles

OMNS - Shingles can be cleared up by using a safe, convenient, inexpensive, nonprescription treatment of vitamin C. Vitamin C is anti-viral and anti-toxin and inactivates the virus that causes shingles. If you have shingles and want relief, you can try this:

Go to a discount store and buy a large bottle of 1000 mg vitamin C tablets. The cost should be less than $15.

Begin when you wake in the morning by taking 3000 mg of vitamin C every 30 minutes and continue until you have a single episode of loose stool (not quite diarrhea). If you haven't had loose stool after 15 hours on this dosage, increase the vitamin C to 4000 mg every 30 minutes.

After you have a loose bowel movement, reduce the dosage to 2000 mg of vitamin C taken every hour. You will quickly find the dosage that is right for you. Adjust the dosage of vitamin C downward to stay below the dosage that will cause loose stool and adjust it upward to relieve shingles symptoms. Continue the oral vitamin C therapy until the shingles disappear.

It sounds too simple to be true, doesn't it? But it works in the majority of cases, as recently reconfirmed by Thomas E. Levy, M.D., J.D. (1)

Sometimes it's necessary to take vitamin C intravenously (IV) for massive shingles outbreaks. (2) Much higher concentrations of vitamin C in the blood can be achieved intravenously than when taken orally. As early as 1950, the medical literature reported that one physician had confirmed intravenous vitamin C curing shingles in 327 patients within 72 hours. (3) Ask your doctor if he or she offers vitamin C IV and, if not, ask friends or search the Internet to find a doctor or facility that does offer this treatment.

Vitamin C blood serum levels of individuals fall during periods of high stress and they develop sub-clinical scurvy (depleted vitamin C levels). This situation can set the stage for a shingles attack.

Remember, a vitamin can act as a drug, but a drug can never act as a vitamin.
With vitamin therapy, at any given quantity, frequently divided doses are more effective than one large single dose.

The reason one nutrient can cure so many different illnesses is because a deficiency of one nutrient can cause many different illnesses.

What is Orthomolecular Medicine? Continue reading >>

Narrator: A person afflicted with the disease has inherited two sickle cell genes from his parents. This realization, that the two genes manufacture the abnormal hemoglobin, set the stage for Dr. Pauling's entry into the field of molecular medicine.

Dr. Pauling: Well, when Doctors Itano, Singer, and Wells, and I published our paper in 1949, we gave it the title: "Sickle Cell Anemia: A Molecular Disease." Now of course, in fact, one might say that any inborn error of metabolism, any hereditary disease, is a molecular disease because it involves an abnormal gene. And the gene we know, almost certainly, is a molecule of DNA, deoxyribose nucleic acid.

The abnormal molecule of deoxyribose nucleic acid that is inherited by the child, prospective patient, causes the trouble for him, and the hereditary disease is accordingly a molecular disease.

NOBEL PRIZE WINNER AND SEVEN OTHER GIANTS OF MEDICINE INDUCTED INTO THE ORTHOMOLECULAR MEDICINE HALL OF FAME

(Toronto, May 14, 2005) Eight giants in the field of medicine, who were advocates of the use of nutrition in the treatment of cancer, were inducted in the Orthomolecular Medicine Hall of Fame on May 14, 2005 at a special reception held at the Fairmont Château Laurier in Ottawa, Canada.

The annual induction ceremony is one of the highlights at The International Society for Orthomolecular Medicine (ISOM) 34th Annual International Conference, Nutritional Medicine Today, which this year met in Canada's capital and at which leading physicians and scientists from around the world gather to discuss ground-breaking studies in nutritional medicine, cardiovascular disease, oncology and mental health.

All inductees, whose seminal work has been influential in the medical and scientific worlds, are pioneers in their respective fields and include the Nobel Prize winner who discovered vitamin C, and numerous advocates of Vitamin C Therapy especially with respect to cancer treatment. The 2005 inductees are: Emanuel Cheraskin, MD, DMD; Max Gerson, MD; David Horrobin, MD, PhD; Josef Issels, MD; Frederick Klenner, MD; Cornelius Moerman, MD; Hugh Desaix Riordan, MD and Nobel Prize Winner Albert Szent-Gyorgi, PhD.

Although they have now passed away, their contributions to the betterment of mankind have been significant and will live long after them. Members of their families and colleagues were on hand to join in the acknowledgment and celebration of their life's work.

Dr. Cheraskin, who, for decades, headed the Department of Oral Medicine at the School of Dentistry at the University of Alabama was among the very first to recognize and demonstrate that oral health indicates total body health.

Dr. Horrobin was Medical Adviser and President of the Schizophrenia Association of Great Britain and his study of human physiology lead him to investigate the role of fatty acids and their derivatives in human disease and to investigate the therapeutic potential of lipids in medicine.

Dr. Max Gerson, began observing that cancer could be cured with nutrition in tandem with systemic detoxification. Albert Schweitzer stated that Dr. Gerson was one of the most eminent geniuses in medical history, while Prince Charles who knew of a terminally ill patient who had undergone Gerson Therapy and is alive and well remarked that "rather than dismissing such experiences, we should further investigate the beneficial nature of these treatments."

Dr. Issels also believed that good nutrition and a clean environment were central to his cancer therapy and felt that cancer was the ultimate symptom of a lifetime of immune system damage which had created an environment for a tumor to grow while conventional therapy just looked at the tumor without recognizing this longtime preconditioning period.

Dr. Klenner asserted that vitamin C is the safest substance available to the physician and was the first doctor to emphasize that small amounts of ascorbic acid do not work and that only adequate uses and huge doses of vitamin C will provide results.

Dr. Moerman's name remains symbolic in the Netherlands as a leader in nutritional therapy for the treatment of cancer as he also believed that strengthening the immune system by proper nutrition was the answer to this disease.

Dr. Hugh Riordan was the first to demonstrate how large doses of vitamin C are chemotherapeutic for cancer patients and his vitamin C intravenous chemotherapy studies are being continued at the University of Kansas and at McGill University in Montreal.

Albert Szent-Gyorgyi, PhD, won the 1937 Nobel Prize in Medicine for his discovery of vitamin C. In fact, it was he who named the vitamin ascorbic acid and first predicted its use in cancer treatment.

Last year, the first inductees to the Orthomolecular Medicine Hall of Fame included double Nobel Prize laureate LINUS PAULING, PhD; WILLIAM KAUFMAN, MD, PhD; WILLIAM J. McCORMICK, MD; EVAN SHUTE MD and WILFRID SHUTE, MD; ALAN COTT, MD; HUMPHRY OSMOND, MD; CARL PFEIFFER, MD, PhD; IRWIN STONE and ROGER J. WILLIAMS, PhD. Continue Reading >>

MOST DIETS NEED SUPPLEMENTATION - Even "Good" Ones

Most illness is due fundamentally to malnutrition. This not only includes the chronic diseases, but also viral and bacterial acute illnesses, which are greatly aggravated by inadequate nutrition. The usual US diet provides an insufficient amount of vitamins to maintain optimal health. And the evidence base for the clinical effects of vitamins is increasing rapidly.

Only 3 percent of a large sampling of U.S. adults practices what is commonly considered a healthy lifestyle. An American Medical Association survey of 153,000 men and women between the ages of 18 and 74 found that only 23.3 percent reported consuming five servings of fruits and vegetables per day. [1] New federal nutritional guidelines specify a minimum of nine servings of fruits and vegetables per day. [2] Many Americans find that consuming the minimum quantities of fruits and vegetables each day is impractical, and appear unable to provide the needed nutrition for themselves and their families. An alternative is to eat all the fruits and vegetables possible, and supplement with a multivitamin/multi-mineral, 400 IU of vitamin E and 1000 mg of vitamin C. [3] A better alternative is to supplement twice a day after meals.

The usual U.S. diet provides an insufficient amount of vitamins. [4] Yet decades of scientific evidence has shown that vitamins, especially vitamin C and vitamin E, are of the utmost importance to human health.

Two-time Nobel Prize winner Dr. Linus Pauling was among the first to realize vitamin C's crucial importance in the maintenance of a healthy immune system. In 1970 he proposed that regular intake of vitamin-C in amounts far higher than the Recommended Daily Allowance (RDA) could help prevent and shorten the duration of the common cold. Although the medical establishment immediately voiced their strong opposition to this idea, many ordinary people believed Dr. Pauling and began taking large amounts of vitamin-C. Most people immediately noticed a great decrease in the frequency and severity of their colds. [5] Continue Reading >>

Vitamin C Fights Heart Disease

Millions die each year from heart disease and stroke, and the overwhelming evidence is that vitamin C supplementation would save many lives.

Two-time Nobel Prize winner Dr. Linus Pauling estimated that the rate of heart disease would be reduced by 80 per cent if adults in the US supplemented with 2,000 to 3,000 mg of vitamin C each day. According to Dr. Pauling, "Since vitamin C deficiency is the common cause of human heart disease, vitamin C supplementation is the universal treatment for this disease."[1] Heart disease is the number one killer in the US. For those with existing heart disease Dr. Pauling said that blockage of heart arteries could actually be reversed by supplementing with 6,000 of vitamin C and 6,000 of lysine (a common amino acid) taken in divided doses throughout the day. Vitamin C supplementation both lowers serum cholesterol levels and repairs lesions of arterial walls. 1998 Nobel Prize winner Dr. Louis J. Ignarro found that supplementing with vitamin C and vitamin E significantly reduces the risk of developing arteriosclerosis.[2]

A study examined vitamin E and vitamin C supplement use in relation to mortality risk in 11,178 persons aged 67-105 who participated in the Established Populations for Epidemiologic Studies of the Elderly over a nine year period.[3] Simultaneous use of vitamins E and C was associated with a lower risk of total mortality and coronary mortality after adjusting for alcohol use, smoking history, aspirin use, and medical conditions.

A landmark study following over 85,000 nurses over a 16-year period for a total of 1,240,000 person-years found that vitamin C supplementation significantly reduced the risk of heart disease.[4] Intake of vitamin C from foods alone was insufficient to significantly effect the rate of heart disease. High quantities of vitamin C from supplements was essential to provide the protective effects. The study adjusted for age, smoking, and a variety of other coronary risk factors.

An international team pooled data from nine prospective studies of 293,000 people that included information on intakes of vitamin E, carotenoids, and vitamin C, with a 10-year follow-up to check for major incident coronary heart disease events in people without disease when the study began. Dietary intake of antioxidant vitamins was only weakly related to a reduced coronary heart disease risk. However, subjects who took as little as 700 mg of vitamin C daily in supplement form reduced their risk of heart disease events by 25 per cent compared to those who took no supplements. [5] Read the full story>>

Vitamin E: Safe, Effective, and Heart-Healthy

Heart disease is the number one killer in the United States, and the evidence supporting vitamin E's efficacy in preventing and reversing heart disease is overwhelming.

Two landmark studies published in the New England Journal of Medicine [1][2] followed a total of 125,000 men and women health care professionals for a total of 839,000 person study-years. It was found that those who supplement with at least 100 IU of vitamin E daily reduced their risk of heart disease by 59 to 66%.

The studies were adjusted for life-style differences (smoking, physical activity, dietary fiber intake, aspirin use) in order to determine the heart effect of vitamin E supplementation alone. Because a diet high in foods containing vitamin E as compared to the average diet further showed only a slight heart-protective effect, the authors emphasized the necessity of vitamin E supplementation.

Researchers at Cambridge University [3] in England reported that patients who had been diagnosed with coronary arteriosclerosis could lower their risk of having a heart attack by 77% by supplementing with 400 IU to 800 IU per day of the natural (d-alpha tocopherol) form of vitamin E.

Pioneer vitamin E researchers and clinicians Drs. Wilfrid and Evan Shute treated some 30,000 patients over several decades and found that people in average health received maximum benefit from 800 IU of the d-alpha tocopherol form of vitamin E. Vitamin E has been proven effective in the prevention and treatment of many heart conditions. "The complete or nearly complete prevention of angina attacks is the usual and expected result of treatment with alpha tocopherol" according to Wilfrid Shute, M. D., a cardiologist. Shute prescribed up to 1,600 IU of vitamin E daily and successfully treated patients for acute coronary thrombosis, acute rheumatic fever, chronic rheumatic heart disease, hypertensive heart disease, diabetes mellitus, acute and chronic nephritis, and even burns, plastic surgery and mazoplasia. Read the full story>>

Study Shows Vitamin "Pill-Poppers" Are Healthier

(OMNS November 2, 2007) New research indicates that NOT taking supplements may be harmful to your health, and that a single daily multi-vitamin is inadequate.

A study of hundreds of persons who take a number of different dietary supplements has found that the more supplements they take, the better their health is.

The study authors reported that a "greater degree of supplement use was associated with more favorable concentrations of serum homocysteine, C-reactive protein, high-density lipoprotein cholesterol, and triglycerides, as well as lower risk of prevalent elevated blood pressure and diabetes." Supplement use results in higher levels of nutrients in the blood serum, and produces "optimal concentrations of chronic disease-related biomarkers." [1] Read the full story>>