Showing posts with label supplements. Show all posts
Showing posts with label supplements. Show all posts

Saturday, July 19, 2008

Study finds high incidence of vitamin D insufficiency in breast cancer survivors

In article published in the July, 2008 issue of the American Journal of Clinical Nutrition, scientists at the Fred Hutchinson Cancer Research Center in Seattle, the National Cancer Institute, and other research centers report a high incidence of vitamin D insufficiency and deficiency among female breast cancer survivors.

The current study utilized data from 790 participants in the multiethnic Health, Eating, Activity, and Lifestyle (HEAL) study of breast cancer patients, which sought to determine the effect of diet, hormones, and other factors on breast cancer prognosis and survival. Blood samples collected within three years following the participants’ breast cancer diagnosis were analyzed for serum 25-hydroxyvitamin D levels, the primary biomarker used to evaluate vitamin D status. Dietary questionnaires were used to obtain information concerning vitamin D intake levels from food and supplements. Continue Reading

Sunday, July 6, 2008

Some genetic defects treatable with supplements

An article published early online on June 3, 2008 in the Proceedings of the National Academy of Sciences reports the prediction of Jasper Rine and colleagues at the University of California, Berkeley that soon-to-be-available personalized genome sequencing will uncover minor genetic flaws that can easily be corrected with nutrition, enabling people to personalize their supplement routine.

"Headlines for the last 20 years have really been about the triumph of biomedical research in finding disease genes, which is biologically interesting, genetically important and frightening to people who get this information," Dr Rine. "I became obsessed with trying to decide if there is some other class of information that will make people want to look at their genome sequence."Variations in genes responsible for the production of enzymes involved in metabolism affect the efficiency of these enzymes.


While having two copies of a defective gene can result in one of many rare metabolic diseases that can be treated with vitamin supplements, many individuals have only one copy, or have two copies of only slightly defective genes, whose subtle effects on enzymes, Dr Rine’s team found, could also be remedied by vitamin supplementation. The current study examined one human enzyme, methylenetetrahydrofolate reductase (MTHFR), which requires the B vitamin folate to function properly.


The enzyme plays a role in DNA nucleotide synthesis. Among 564 individuals, 3 common variants and 11 minor, uncommon genetic variants of MTHFR were found. When these gene variants were synthesized and inserted into yeast cells, the most common variant and 4 of the uncommon variants were found to affect the enzyme's function, yet supplementation of the yeast with folate restored full functionality to all but one of these. Continue Reading

Monday, June 23, 2008

When Oxidants Can Increase Risk of Death

1. When Antioxidants Can Increase Risk of DeathThe truth about these nutrients - their benefits and risks

Antioxidants have long been considered good news, helping to reduce the 'oxidative' damage caused by everyday living that ages and eventually kills us. We are encouraged to eat foods (especially our 'five a day') that provide rich sources of antioxidant nutrients, and a massive market for antioxidant supplements has sprung up with literally thousands of studies to affirm their benefits.

But in the last few years, a number of big trials have apparently shown that taking extra antioxidants in the form of supplements doesn't work. They have reported that antioxidants, far from staving off the big killers such as cancer and heart disease, can actually make them worse. A recent review of a number of studies gave rise to media headlines such as "Antioxidants can kill".

So what is going on?
After numerous studies that showed extra antioxidants reduced risk of disease, some more recent research started to look at their effect on two particular 'at-risk' groups - people who smoked and those with cardiovascular disease.

Several of these trials showed that the risk of cancer in smokers increased slightly when they were given beta-carotene. Other studies suggested a small increased risk of heart attack in heart patients who were on medications such as statins and taking vitamin E.
What's interesting to note, however, is that far from putting the nail in the coffin of antioxidants, these studies give us an interesting insight into how these nutrients work - and why people who smoke or take statins are at risk, unless they adapt (rather than stop) their supplement intake.
For example, the recent Cochrane Review by Bjelakovic et al actually found that people who took BOTH multivitamin AND antioxidant supplements showed no increased risk, and in some cases, a significant decrease in risk. Now why should that be, and what does it tell us about the way antioxidants work?

I believe it points to a simple explanation as to why high-dose vitamin E increases cardiovascular risk, why beta-carotene increases smokers' risk, and why multivitamins eradicate this risk.
With this month's 100%health newsletter, I have produced a Special Report which looks in detail as these issues.

Find out:
. Why statins make high-dose vitamin E dangerous
. The nutrients that can reduce disease risk for smokers
. Why the Cochrane review is flawed
. The reactions to the review's findings from scientists whose studies were included
. The positive findings that went unreported
. And most importantly, what you can do to protect yourself - whether you're taking statins or smoking, are elderly or young, in good health or bad.

Click here to make sure you receive your copy.
My July newsletter also tackles the controversial issue of Childhood Vaccinations and looks at the evidence behind the guidelines so many parents are questioning.
I'll also be exploring the latest research into anti-ageing to bring you the best tips to help you turn the clock back and stay youthful.

And there's another Special Report on the plant compounds Salvestrols - a new discovery that could provide a major breakthrough in the prevention and treatment of cancer.
To ensure you receive all this - plus a whole range of exclusive member benefits - click here to join 100%health.

2. Two days is all it takes to change your life. Book now to qualify for Early Bird discounts
Learn how to build up your energy, control your weight and beat nagging problems that plague your health.

Our ever popular 100%health Weekend Workshop will give you manageable tools to combat the obstacles in your life that are holding you back. All you need is the desire and determination to transform your life. We do the rest by tailor-making a new life plan for you.

The next workshop is on 27th/28th September in London and I will spend two days taking you through a step-by-step guide to the eight key areas that will lead you to optimum health including information on the best foods to eat, why eating low-GL is best, cookery demonstrations and a personalised Health Action Plan. Plus a follow-up online health assessment to help you track your progress.

What you'll achieve
By the end of the weekend you will know exactly what you need to do to achieve the boundless energy, sharp mind, balanced mood, stable weight and glowing skin that are the hallmark of great health. We give you the tools to do it and the confidence to follow it through.
Book today and take the first step. I very much hope you will join me on the next 100%health Workshop in London on 27th/28th September. Places strictly limited - book your ticket now to qualify for the Early Bird discount of £50! Click here for more details and how to book.
Don't forget - if you're a member of 100%health you'll automatically save a further £30 on your booking - click here to join.

3. Are you interested in becoming a nutritional therapist?
The Institute for Optimum Nutrition offers a 3-year part time foundation science degree in nutritional therapy.

If you are interested in studying nutrition to qualify as a nutritional therapist , the Institute for Optimum Nutrition have asked me to let you know there are still some places available on their excellent course commencing this September. To find out more book your place on one of the remaining open days see the ION website for more details: http://www.ion.ac.uk/open_days.htm
Wishing you the best of health,
Patrick Holford

Sunday, June 8, 2008

Breast cancer

The following supplementation regimen is suggested. As always, consult your physician before beginning any nutritional supplementation regimen.

Dual-Action Cruciferous Vegetable Extract With Cat's Claw, 1-2 capsules per day.

Lightly caffeinated green tea extract, three 725 mg capsules, two times a day with meals. Use decaffeinated green tea extract if you are sensitive to caffeine or want to use the less-stimulating version with the evening dosage.
CLA or CLA with Guarana, 3000 to 4000 mg daily of CLA and about 300 mg of guarana, early in the day.

Melatonin, 3 to 50 mg at bedtime.
PhytoFood Powder (broccoli, cabbage, and other cruciferous vegetables that provide sulphoraphane and other cancer-fighting plant extracts), 1-2 tbsp daily.
Se-methylselenocysteine, 200 to 400 mcg daily.
CoQ10, three 100 mg softgels in divided doses. Note the caution stated in this protocol.
Super EPA/DHA w/Sesame Lignans, 8 softgels daily, in divided doses. Take with nonfiber meals.
Vitamin D3, 4000 to 6000 IU taken daily with monthly blood testing to monitor for toxicity. Reduce dosage at 6 months.
Water-soluble vitamin A, 100,000 to 300,000 IU daily with monthly blood testing to monitor for toxicity. Reduce dosage at 6 months (refer to vitamin A precautions in Appendix A). Continue Reading

Tuesday, April 15, 2008

VITAMIN C DOES NOT CAUSE KIDNEY STONES

By Steve Hickey, PhD and Hilary Roberts, PhD.

(OMNS) It is strange how some medical authors seem desperate to show that vitamin C causes harm. One recurrent scare story is that vitamin C might cause kidney stones. However, although such warnings pop up regularly, these reports do not demonstrate an increase in the number or size of stones; instead, they rely on vague indicators of improbable risk.

The authors of such uncritical papers have probably not read the literature, for this is an old story. Decades ago, the idea that vitamin C causes kidney stones formed part of the medical attack on Linus Pauling. While it was initially a reasonable hypothesis, unexpected kidney stones are not found in people taking large amounts of vitamin C. (1,2)

There is no evidence that vitamin C causes kidney stones. Indeed, in some cases, high doses may be curative. (3) A recent, large-scale, prospective study followed 85,557 women for 14 years and found no evidence that vitamin C causes kidney stones. (4) There was no difference in the occurrence of stones between people taking less than 250 milligrams per day and those taking 1.5 grams or more. This study was a follow up of an earlier study on 45,251 men. This earlier study indicated that doses of vitamin C above 1.5 grams reduce the risk of kidney stones. (5) The authors of these large studies stated that restriction of higher doses of vitamin C because of the possibility of kidney stones is unwarranted.

People with recurrent stone formation may have an unusual biochemistry, leading to increased production of oxalate from vitamin C. (6) Oxalate and urate can accumulate in kidney stones. In practice, there is an increased excretion of both oxalate and urate with gram level doses of vitamin C (ascorbate). Various authors over the years have used this increase to predict that vitamin C will cause kidney stones; however, these predictions have never been confirmed.

Around three quarters of all kidney stones are composed of calcium oxalate; unlike some other stone types, these can form in acidic urine. Although vitamin C does increase the production of oxalate in the body, there is no evidence that it increases stone formation. It could even have the reverse effect, for several reasons. Firstly, vitamin C tends to bind calcium, which could decrease its availability for formation of calcium oxalate. Secondly, vitamin C has a diuretic action: it increases urine flow, providing an environment that is less suitable for formation of kidney stones. Finally, stone formation appears to occur around a nucleus of infection. High concentrations of vitamin C are bactericidal and might prevent stone formation by removing the bacteria around which stones form.

Vitamin C could also prevent other types of kidney stones. Less common forms of stone include uric acid stones (8%), that form in gout, and cystine stones (1%), which can occasionally be formed in children with a hereditary condition; these stones are not side effects of vitamin C. Other stones include those made from calcium phosphate (5%), which dissolve in a vitamin C solution. Acid urine, produced by ascorbate, will also dissolve the struvite stones (magnesium ammonium phosphate) that often occur in infected urine.

Recently, Linda Massey and colleagues from Washington State University have claimed that vitamin C increases the risk of kidney stones. (7) Their paper illustrates how the claims of risk have little basis in fact. Massey claims that vitamin C supplementation can increase the amount of oxalate. Vitamin C can increase oxalate absorption and, if degraded in the body, ascorbate can be converted into oxalate. However, while oxalate is a constituent of some types of kidney stone, an increase in its concentration does not mean that more or larger kidney stones will be formed. The formation of kidney stones is influenced by many factors and, as we have seen, vitamin C might be predicted to inhibit several aspects of stone generation. Massey suggests that this increase in oxalate may increase the risk of stones. This is a weak suggestion, which is contradicted by substantial evidence, quoted above. Continue reading >>

Wednesday, April 9, 2008

Treatment Protocol for Alcoholism

A Message from Abram Hoffer, M.D., Ph.D.:

"Ever since I met Bill W, the cofounder of Alcoholics Anonymous and we became close friends, I have had a personal interest in the treatment of alcoholism.

Bill taught that there were three components to the treatment of alcoholism: spiritual, mental and medical. AA provided a spiritual home for alcoholics that many could not find anywhere else and helped them sustain abstinence. But for many AA alone was not enough; not everyone in AA had achieved a comfortable sobriety. Bill recognized that the other two components were important. When he heard of our use of niacin for treating alcoholics, he became very enthusiastic about it because niacin gave these unfortunate patients immense relief from their chronic depression and other physical and mental complaints.

"Niacin is the most important single treatment for alcoholism, and it is one of the most reliable treatments. And it is safe, much safer than any of the modern psychiatric drugs. Niacin does not work as well when alcoholics are still drinking but in a few cases it has decreased the intake of alcohol until they were abstinent. This conclusion is based on the work my colleagues and I have done since 1953.

"I know of many alcoholics who did not want to stop drinking, but did agree to take niacin. Over the years, they gradually were able to reduce their intake until they brought it under control. Some alcoholics can even become social drinkers on a very small scale. I have not found many who could. But I think that if started on the program very early, many more could achieve normalcy. I suspect that treatment centers using those ideas will be made available one day, and will be much more successful than the standard treatment today. This all too often still consists of dumping them into hospitals and letting them dry out, with severe pain and suffering. When they are discharged, most go right back to the alcohol, the most dangerous and widely used street drug available without a prescription. Continue reading >>

Thursday, April 3, 2008

MOST DIETS NEED SUPPLEMENTATION - Even "Good" Ones

Most illness is due fundamentally to malnutrition. This not only includes the chronic diseases, but also viral and bacterial acute illnesses, which are greatly aggravated by inadequate nutrition. The usual US diet provides an insufficient amount of vitamins to maintain optimal health. And the evidence base for the clinical effects of vitamins is increasing rapidly.

Only 3 percent of a large sampling of U.S. adults practices what is commonly considered a healthy lifestyle. An American Medical Association survey of 153,000 men and women between the ages of 18 and 74 found that only 23.3 percent reported consuming five servings of fruits and vegetables per day. [1] New federal nutritional guidelines specify a minimum of nine servings of fruits and vegetables per day. [2] Many Americans find that consuming the minimum quantities of fruits and vegetables each day is impractical, and appear unable to provide the needed nutrition for themselves and their families. An alternative is to eat all the fruits and vegetables possible, and supplement with a multivitamin/multi-mineral, 400 IU of vitamin E and 1000 mg of vitamin C. [3] A better alternative is to supplement twice a day after meals.

The usual U.S. diet provides an insufficient amount of vitamins. [4] Yet decades of scientific evidence has shown that vitamins, especially vitamin C and vitamin E, are of the utmost importance to human health.

Two-time Nobel Prize winner Dr. Linus Pauling was among the first to realize vitamin C's crucial importance in the maintenance of a healthy immune system. In 1970 he proposed that regular intake of vitamin-C in amounts far higher than the Recommended Daily Allowance (RDA) could help prevent and shorten the duration of the common cold. Although the medical establishment immediately voiced their strong opposition to this idea, many ordinary people believed Dr. Pauling and began taking large amounts of vitamin-C. Most people immediately noticed a great decrease in the frequency and severity of their colds. [5] Continue Reading >>

Tuesday, April 1, 2008

Vitamin C Fights Heart Disease

Millions die each year from heart disease and stroke, and the overwhelming evidence is that vitamin C supplementation would save many lives.

Two-time Nobel Prize winner Dr. Linus Pauling estimated that the rate of heart disease would be reduced by 80 per cent if adults in the US supplemented with 2,000 to 3,000 mg of vitamin C each day. According to Dr. Pauling, "Since vitamin C deficiency is the common cause of human heart disease, vitamin C supplementation is the universal treatment for this disease."[1] Heart disease is the number one killer in the US. For those with existing heart disease Dr. Pauling said that blockage of heart arteries could actually be reversed by supplementing with 6,000 of vitamin C and 6,000 of lysine (a common amino acid) taken in divided doses throughout the day. Vitamin C supplementation both lowers serum cholesterol levels and repairs lesions of arterial walls. 1998 Nobel Prize winner Dr. Louis J. Ignarro found that supplementing with vitamin C and vitamin E significantly reduces the risk of developing arteriosclerosis.[2]

A study examined vitamin E and vitamin C supplement use in relation to mortality risk in 11,178 persons aged 67-105 who participated in the Established Populations for Epidemiologic Studies of the Elderly over a nine year period.[3] Simultaneous use of vitamins E and C was associated with a lower risk of total mortality and coronary mortality after adjusting for alcohol use, smoking history, aspirin use, and medical conditions.

A landmark study following over 85,000 nurses over a 16-year period for a total of 1,240,000 person-years found that vitamin C supplementation significantly reduced the risk of heart disease.[4] Intake of vitamin C from foods alone was insufficient to significantly effect the rate of heart disease. High quantities of vitamin C from supplements was essential to provide the protective effects. The study adjusted for age, smoking, and a variety of other coronary risk factors.

An international team pooled data from nine prospective studies of 293,000 people that included information on intakes of vitamin E, carotenoids, and vitamin C, with a 10-year follow-up to check for major incident coronary heart disease events in people without disease when the study began. Dietary intake of antioxidant vitamins was only weakly related to a reduced coronary heart disease risk. However, subjects who took as little as 700 mg of vitamin C daily in supplement form reduced their risk of heart disease events by 25 per cent compared to those who took no supplements. [5] Read the full story>>

Monday, March 31, 2008

Vitamin E: Safe, Effective, and Heart-Healthy

Heart disease is the number one killer in the United States, and the evidence supporting vitamin E's efficacy in preventing and reversing heart disease is overwhelming.

Two landmark studies published in the New England Journal of Medicine [1][2] followed a total of 125,000 men and women health care professionals for a total of 839,000 person study-years. It was found that those who supplement with at least 100 IU of vitamin E daily reduced their risk of heart disease by 59 to 66%.

The studies were adjusted for life-style differences (smoking, physical activity, dietary fiber intake, aspirin use) in order to determine the heart effect of vitamin E supplementation alone. Because a diet high in foods containing vitamin E as compared to the average diet further showed only a slight heart-protective effect, the authors emphasized the necessity of vitamin E supplementation.

Researchers at Cambridge University [3] in England reported that patients who had been diagnosed with coronary arteriosclerosis could lower their risk of having a heart attack by 77% by supplementing with 400 IU to 800 IU per day of the natural (d-alpha tocopherol) form of vitamin E.

Pioneer vitamin E researchers and clinicians Drs. Wilfrid and Evan Shute treated some 30,000 patients over several decades and found that people in average health received maximum benefit from 800 IU of the d-alpha tocopherol form of vitamin E. Vitamin E has been proven effective in the prevention and treatment of many heart conditions. "The complete or nearly complete prevention of angina attacks is the usual and expected result of treatment with alpha tocopherol" according to Wilfrid Shute, M. D., a cardiologist. Shute prescribed up to 1,600 IU of vitamin E daily and successfully treated patients for acute coronary thrombosis, acute rheumatic fever, chronic rheumatic heart disease, hypertensive heart disease, diabetes mellitus, acute and chronic nephritis, and even burns, plastic surgery and mazoplasia. Read the full story>>

Thursday, March 27, 2008

Study Shows Vitamin "Pill-Poppers" Are Healthier

(OMNS November 2, 2007) New research indicates that NOT taking supplements may be harmful to your health, and that a single daily multi-vitamin is inadequate.

A study of hundreds of persons who take a number of different dietary supplements has found that the more supplements they take, the better their health is.

The study authors reported that a "greater degree of supplement use was associated with more favorable concentrations of serum homocysteine, C-reactive protein, high-density lipoprotein cholesterol, and triglycerides, as well as lower risk of prevalent elevated blood pressure and diabetes." Supplement use results in higher levels of nutrients in the blood serum, and produces "optimal concentrations of chronic disease-related biomarkers." [1] Read the full story>>

Friday, March 21, 2008

Vitamins Reduce the Duration and Severity of Influenza

(OMNS, March 19, 2008) Vitamins fight the flu by boosting the body’s own immune response and by accelerating healing. Individuals can be better prepared for an influenza epidemic by learning how to use vitamin supplements to fight off ordinary respiratory infections. The most important vitamins are vitamins C, D, niacin, and thiamine.

Vitamin D Vitamin D has known anti-viral properties [1] and has been directly associated with fighting influenza in a recent scientific review. [2] Extensive evidence now shows that vitamin D serves as an important regulator of immune system responses. [3] The most dramatic evidence is a recent double-blind trial proving that vitamin D prevents cancers [4], supported by two recent epidemiological studies. [5,6] Vitamin D has been part of a supplement combination proven effective against HIV in a recent double-blind trial. [7]

During a viral infection, the body can draw on vitamin D stored in the body to supply the increased needs of the immune system. The withdrawn supplies of vitamin D are quickly replenished with 4,000 to 10,000 IU/day doses for a few days. Due to biochemical individuality, we recommend vitamin D blood testing as a routine part of a yearly physical exam.

Niacin Niacin has known anti-viral properties. The most persuasive evidence comes from recent work with HIV patients.[8-12] Niacin is required for cells to generate the energy they use to perform virtually all biological functions.

Niacin’s effectiveness fighting viruses may have to do with accelerating wound healing as well as improving immunity. Accelerating tissue repair limits collateral damage and minimizes the risk of secondary infection. Niacin has been proven to promote healing of damaged skin in double-blind trials. [13] Other recent findings (niacin reduces injury to the brain after strokes and reduces inflammation in general) also provide evidence of healing. [14,15] Read the full story >>

Thursday, March 20, 2008

JOURNAL OF ORTHOMOLECULAR MEDICINE NOW ONLINE

(OMNS February 29, 2008) The archives of the Journal of Orthomolecular Medicine are now posted online. Past issues from 1967 through 2002 are available for downloading, at no charge, at http://orthomolecular.org/library/jom/index.shtml

"36 years of important material is now freely available to everyone," said Steven J. Carter, Executive Director of the Toronto-based International Schizophrenia Foundation, which publishes the Journal.

The Journal of Orthomolecular Medicine has led the way in presenting, in advance of other medical journals, new health concerns and treatments including niacin therapy for schizophrenia and coronary disease; vitamin C for cancer; and the nutritional treatment of behavioral disorders, and drug and alcohol abuse. The JOM was also the first medical journal to publish papers on the nutritional treatment of allergies, autism, and AIDS. JOM published pioneering research on candiasis in 1978, mercury amalgam toxicity in 1982, and chronic fatigue syndrome in 1988. The Journal has published over 100 papers on nutritional medicine and cancer, and over 400 articles on schizophrenia and other psychiatric illnesses. JOM is peer-reviewed.

The Journal was founded in 1967 as the Journal of Schizophrenia, and subsequently titled the Journal of Orthomolecular Psychiatry until 1986. Nobel Laureate Linus Pauling authored 9 papers in the Journal from 1970-1992. It was Pauling that gave nutritional medicine the name "orthomolecular." Says JOM Editor-in Chief Abram Hoffer, MD, PhD: "In 1968, Dr. Pauling proposed the term orthomolecular (1,2) which we recognized as the correct word to define the total interest in nutrition, clinical ecology, and the use of vitamin and mineral supplements. All the pioneers in orthomolecular medicine have reported their findings in this journal. It thus represents a unique source for these earlier and current studies which provide a basis for the increasing growth of nutritional medicine." Continue the full article >>

Wednesday, March 19, 2008

Vitamin Supplementation Prevents Anorexia

(OMNS February 9, 2008) Anorexia is primarily due to vitamin deficiency. Approximately one in twenty teenage girls in America is struggling with an eating disorder. Parents can help eliminate the risk of anorexia by providing their children with vitamin supplements.

Anorexia is an acknowledged clinical marker of beriberi, the disease specifically caused by a deficiency of vitamin B1 (thiamine). [1] Anorexia is also commonly observed as an early symptom of pellagra (niacin deficiency) [2] and is a known complication of scurvy, vitamin C deficiency. [3] Prevention is especially important, because beriberi/anorexia often does not respond well even to treatment with high doses of thiamine for months, and sometimes does not respond at all. [1] But as a rule, high potency vitamin supplements are an effective cure for the loss of muscle mass caused by beriberi and the skin lesions caused by pellagra.

The vitamin B1 in almost every multivitamin and B-complex vitamin pill is either thiamine mononitrate or thiamine hydrochloride. The body’s ability to absorb these two forms of thiamine is limited [4] by the maximum amount that can be handled by the body’s two specialized thiamine transport proteins. [5]. This means many doses per day of oral thiamine are necessary for effective treatment. Another class of thiamine molecules, called allithiamines, are much better absorbed. [6] Since allithiamines are not included in standard multivitamin preparations, we recommend their reformulation to include this specific form of B1.

The conventional medical approach to eating disorders such as anorexia typically includes psychological/behavioral treatment, medication, and food-groups dietetics. It is surprisingly rare for physicians to link eating disorders with vitamin deficiency, and few doctors recommend vitamin supplements for prevention. Continue the full article

Tuesday, March 18, 2008

Prenatal vitamins shown to reduce children's risk of cancer

M.T. Whitney Key concepts: folic acid, vitamins and prenatal vitamins

(NaturalNews) Taking folic acid and multivitamins while pregnant can nearly halve the chance of a child getting a common cancer before the age of 18, new evidence from a Toronto children's hospital shows.
The study, from Toronto's Hospital for Sick Children, was spurred when officials at the hospital noticed a drop in neuroblastomas five years ago, after the Canadian government started requiring flour manufacturers to add folic acid to their product in 1998.

What you need to know
• Folic acid and multivitamins were shown to lower the chance of leukemia in children by 39 percent.

• The same one-two punch can lower the risk of a child developing a brain tumor by 27 percent.

• The risk of a child getting a neuroblastoma, which attacks the nervous system, was lowered by 49 percent.

• For spina bifida, a spinal condition, the risk is lowered by 80 percent with folic acid supplements.

• Most folic acid supplements, easily found for just pennies a day, will give you between 600 and 1,000 milligrams for the day, more than the government-recommended 400 milligrams.

• Only 40 percent of Canadian mothers take the right amount of folic acid supplements during pregnancy, Dr. Gideon Koren, the study's principal investigator, told The Toronto Star.

• The study was published in the journal Clinical Pharmacology and Therapeutics (February, 2007).

• "To our amazement and surprise, all available studies today from different parts of the world ... showed a similar trend (to the one in Ontario)," Koren told the Toronto Star.

Sadly, most doctors and hospitals still don't teach nutrition to patients, and expectant mothers are rarely told about the multitude of health benefits derived from nutrients like folic acid or vitamin D. The current message on folic acid supplementation focuses solely on spina bifida and fails to mention the vitamin's anti-cancer effects.


Bottom line
• Mothers who take folic acid and prenatal vitamins may reduce risk of cancer in their children.

Sunday, March 16, 2008

How Vitamin C Stops Cancer

ScienceDaily (Sep. 12, 2007) — Nearly 30 years after Nobel laureate Linus Pauling famously and controversially suggested that vitamin C supplements can prevent cancer, a team of Johns Hopkins scientists have shown that in mice at least, vitamin C - and potentially other antioxidants - can indeed inhibit the growth of some tumors ¯ just not in the manner suggested by years of investigation.

The conventional wisdom of how antioxidants such as vitamin C help prevent cancer growth is that they grab up volatile oxygen free radical molecules and prevent the damage they are known to do to our delicate DNA. The Hopkins study, led by Chi Dang, M.D., Ph.D., professor of medicine and oncology and Johns Hopkins Family Professor in Oncology Research, unexpectedly found that the antioxidants' actual role may be to destabilize a tumor's ability to grow under oxygen-starved conditions. Their work is detailed this week in Cancer Cell.

"The potential anticancer benefits of antioxidants have been the driving force for many clinical and preclinical studies," says Dang. "By uncovering the mechanism behind antioxidants, we are now better suited to maximize their therapeutic use."

"Once again, this work demonstrates the irreplaceable value of letting researchers follow their scientific noses wherever it leads them," Dang adds.

The authors do caution that while vitamin C is still essential for good health, this study is preliminary and people should not rush out and buy bulk supplies of antioxidants as a means of cancer prevention.
The Johns Hopkins investigators discovered the surprise antioxidant mechanism while looking at mice implanted with either human lymphoma (a blood cancer) or human liver cancer cells. Both of these cancers produce high levels of free radicals that can be suppressed by feeding the mice supplements of antioxidants, either vitamin C or N-acetylcysteine (NAC).

However, when the Hopkins team examined cancer cells from cancer-implanted mice not fed the antioxidants, they noticed the absence of any significant DNA damage. "Clearly, if DNA damage was not in play as a cause of the cancer, then whatever the antioxidants were doing to help was also not related to DNA damage," says Ping Gao, Ph.D, lead author of the paper.

That conclusion led Gao and Dang to suspect that some other mechanism was involved, such as a protein known to be dependent on free radicals called HIF-1 (hypoxia-induced factor), which was discovered over a decade ago by Hopkins researcher and co-author Gregg Semenza, M.D., Ph.D., director of the Program in Vascular Cell Engineering. Indeed, they found that while this protein was abundant in untreated cancer cells taken from the mice, it disappeared in vitamin C-treated cells taken from similar animals.

"When a cell lacks oxygen, HIF-1 helps it compensate," explains Dang. "HIF-1 helps an oxygen-starved cell convert sugar to energy without using oxygen and also initiates the construction of new blood vessels to bring in a fresh oxygen supply."

Some rapidly growing tumors consume enough energy to easily suck out the available oxygen in their vicinity, making HIF-1 absolutely critical for their continued survival. But HIF-1 can only operate if it has a supply of free radicals. Antioxidants remove these free radicals and stop HIF-1, and the tumor, in its tracks.

The authors confirmed the importance of this "hypoxia protein" by creating cancer cells with a genetic variant of HIF-1 that did not require free radicals to be stable. In these cells, antioxidants no longer had any cancer-fighting power.

The research was funded by the National Institutes of Health.

Authors on the paper are Dean Felsher of Stanford; and Gao, Huafeng Zhang, Ramani Dinavahi, Feng Li, Yan Xiang, Venu Raman, Zaver Bhujwalla, Linzhao Cheng, Jonathan Pevsner, Linda Lee, Gregg Semenza and Dang of Johns Hopkins.

Adapted from materials provided by Johns Hopkins Medical Institutions, via EurekAlert!, a service of AAAS.

Tuesday, March 11, 2008

Treatment Protocol for Alcoholism

A Message from Abram Hoffer, M.D., Ph.D.:

"Ever since I met Bill W, the cofounder of Alcoholics Anonymous and we became close friends, I have had a personal interest in the treatment of alcoholism. Bill taught that there were three components to the treatment of alcoholism: spiritual, mental and medical. AA provided a spiritual home for alcoholics that many could not find anywhere else and helped them sustain abstinence.
But for many AA alone was not enough; not everyone in AA had achieved a comfortable sobriety. Bill recognized that the other two components were important. When he heard of our use of niacin for treating alcoholics, he became very enthusiastic about it because niacin gave these unfortunate patients immense relief from their chronic depression and other physical and mental complaints.

"Niacin is the most important single treatment for alcoholism, and it is one of the most reliable treatments. And it is safe, much safer than any of the modern psychiatric drugs. Niacin does not work as well when alcoholics are still drinking but in a few cases it has decreased the intake of alcohol until they were abstinent. This conclusion is based on the work my colleagues and I have done since 1953.


"I know of many alcoholics who did not want to stop drinking, but did agree to take niacin. Over the years, they gradually were able to reduce their intake until they brought it under control. Some alcoholics can even become social drinkers on a very small scale. I have not found many who could. But I think that if started on the program very early, many more could achieve normalcy. I suspect that treatment centers using those ideas will be made available one day, and will be much more successful than the standard treatment today. This all too often still consists of dumping them into hospitals and letting them dry out, with severe pain and suffering. When they are discharged, most go right back to the alcohol, the most dangerous and widely used street drug available without a prescription.

"Orthomolecular treatment is the treatment of choice. The following protocol for alcoholism outlines the importance of the nutritional factors that have been shown to be very successful on treating this condition. The treatment can be used alone but is best combined with dietary advice and additional nutrients."

The late Dr. Roger Williams, a chemistry professor at the University of Texas and former president of the American Chemical Society, also wrote extensively on the alcoholism.[1] Dr. Williams recommended large doses of vitamins and an amino acid called L-glutamine.
What should the alcoholic do to help stop drinking and return his or her body to normal functioning? Supply the following nutrients to the body:

* Vitamin C to saturation (on the order of 10,000 to 20,000 mg per day and more). High doses of vitamin C chemically neutralize the toxic breakdown products of alcohol metabolism. Vitamin C also increases the liver's ability to reverse the fatty build-up so common in alcoholics.

* To titrate to saturation, take 1000 mg of vitamin C every hour. When saturation is reached, there will be a single episode of diarrhea; then reduce the dosage to 1000 mg every four hours.
* A B50-complex tablet (comprising 50 mg of each of the major B-vitamins, 6 times daily).

* L-Glutamine (2000 or 3000 mg). L-Glutamine is an amino acid that decreases physiological cravings for alcohol. It is one the two primary energy providers that burn glycogen to provide fuel to the brain and stimulates many neurofunctions. L- Glutamine is naturally produced in the liver and kidneys. Alcohol harms the kidneys and liver, thus supplementation is vital (concurrently reducing cravings for sugar and alcohol).
* Lecithin (2 to 4 tablespoons daily). Provides inositol and choline, related to the B-complex. Lecithin also helps mobilize fats out of the liver.

* Chromium (at least 200 to perhaps 400 mcg chromium polynicotinate daily). Chromium greatly reduces carbohydrate mis-metabolism, and greatly helps control blood sugar levels. Many, if not most, alcoholics are hypoglycemic.

* A good high-potency multi-vitamin, multi-mineral supplement as well, containing magnesium (400 mg) and the antioxidants carotene and d-alpha tocopherol.
In summary, the alcoholic’s body needs the proper nutrients in adequate quantities to return to normal metabolic functioning. The above nutrients are safe, effective, inexpensive and available from discount stores or health food stores without prescription. There is not even one death per year from vitamins. Pharmaceutical drugs, properly prescribed and taken as directed, kill over 100,000 Americans annually. Hospital errors kill still more. Most illness is due fundamentally to malnutrition. This not only includes the chronic diseases, but also viral and bacterial acute illness, which are greatly aggravated by inadequate nutrition. Supplements are not the problem; they are the solution. Malnutrition is the problem.

Editorial Review Board:
Abram Hoffer, M.D., Ph.D. Harold D. Foster, Ph.D. Bradford Weeks, M.D. Carolyn Dean, M.D. N.D. Eric Patterson, M.D.Andrew W. Saul, Ph.D.
References;
1, Williams, RJ, Roach, MK, "Impaired and inadequate glucose metabolism in the brain as an underlying cause of alcoholism--an hypothesis.", Proc Natl Acad Sci U S A. 1966 August; 56(2): 566-571.

ACT FOR HEALTH FREEDOM NOW: Go to http://www.friendsoffreedominternational.org/ and purchase "Death by Modern Medicine" and view and purchase the new movie on Codex and Free Trade called "We Become Silent" by Kevin Miller. Proceeds from the sale of these products are crucial to help fund our health freedom action. For state action go to:
http://www.nationalhealthfreedom.org/ . To support HR 4282, the new Health Freedom Protection Act bill that we talked about in our November 7, 2005 article in News With Views “A Call to Action to Protect Free Speech” go to: www.stopfdacensorship.org and send a letter to Congress.

Thursday, March 6, 2008

ORTHOMOLECULAR MEDICINE NEWS SERVICE

"It is a matter of common knowledge that any processing that foods undergo serves to make them more harmful than unprocessed foods." (McDonald's Corporation legal statement, shown in the documentary "Supersize Me")

The DOCTOR YOURSELF NEWSLETTER (Vol. 5, No. 2 for January 5, 2005)

"Free of charge, free of advertising, and free of the A.M.A." Written and copyright 2004 by Andrew W. Saul of http://www.doctoryourself.com/ , which welcomes 1.5 million visitors
annually. Commercial use of the website or the contents of this Newsletter is strictly prohibited.

ORTHOMOLECULAR MEDICINE NEWS SERVICE

My long-time readers have likely taken notice that the DOCTOR YOURSELF Newsletter is now a monthly. Yes, after five years of twice- monthly publication, I am giving a nod to the reality of some 30,000 hits a day at the http://www.doctoryourself.com/ website. There is only so much
time in a day.

The good news: I will continue to assail your ears about every four weeks or so with my edifying editorials and health hints. And, there is still NO CHARGE for the Newsletter. (To subscribe to the Doctor Yourself Newsletter:

newsletter-subscribe@doctoryourself.com )
Here's the really good news: With my copious new free time, I am beginning another project: the ORTHOMOLECULAR MEDICINE NEWS SERVICE. Like the Associated Press or Reuters, OMNS is a wire-service style news feed directed to members of the press, radio and TV news
media.

We have authoritative scientific clout and plan to use it. The OMNS editorial board consists of:

Abram Hoffer, M.D.
Hugh D. Riordan, M.D.
Harold Foster, Ph.D.
Bradford Weeks, M.D.

I see the creation of the Orthomolecular Medicine News Service as an increasingly necessary step to counter the pharmaceutically-biased factoids and vitamin misinformation that the media seem ever so ready to accept uncritically. The recent allegedly-negative E and C studies bear this out. (http://www.doctoryourself.com/safety.html/ )

Now with many hundreds of media email addresses, both newspaper and TV, we will shortly go ahead with a mass e-mail press release and inaugural announcement.

YES, YOU TOO MAY SUBSCRIBE TO THE ORTHOMOLECULAR NEWS SERVICE, free of charge. To do so, you will need to promptly send a blank email to omns-subscribe@doctoryourself.com . (Requests to other addresses, such as my regular email address, will not be processed.)

ASCORBATE: THE SCIENCE OF VITAMIN C
"It's not what we don't know that harms us, but what we do know that ain't so." (Eubie Blake, 1883-1983)

What is it about a little left-handed molecule of six carbons, six oxygens, and eight hydrogens that ticks off so many in the medical community? Maybe it's cases like this one: Ray, a health professional I know, had an 11-month old son who was very sick for over a week. No one, and I mean no one, in their family had had any sleep in a long time.

They were up night after night with this child, who had a high fever, glazed watery eyes, tons of thick watery mucus and labored breathing. The child would not sleep, and did little else but cry. The baby was under the care of a pediatrician, who, in the infant's eleven months on earth, had already prescribed twelve rounds of some very serious antibiotics. That they clearly were not working was all too apparent to Ray, who out of desperation decided to try something he previously had been taught to not try: bowel tolerance quantities of oral ascorbate.

Ray and his wife gave their baby some vitamin C about every 15 minutes. As a result, the baby
was noticeably improved in a matter of hours, and slept through the night. With frequent doses continuing, the child was completely well in 48 hours. Ray calculated that the baby had received just over 2,000 mg vitamin C per kilogram body weight per day. This is even more than what Dr. Frederick Robert Klenner customarily ordered for sick patients. Remarkably, at 20,000 milligrams of vitamin C/day, that 20-pound baby never had diarrhea. With such a little body, you have to marvel at where all of it was going. Of course, it is the opinion of those who promulgate the US RDA and related nutritional mythology that almost all of that baby's vitamin C went uselessly into the toilet. Ray and his wife would tell you differently. They would say
that their sick child soaked it up like a sponge, and then promptly got better.

For the layman unable to obtain intravenous vitamin C, one of the most important parts of Hickey and Roberts' new book, Ascorbate: The Science of Vitamin C, is its attention to oral administration, divided dosing, absorption, and vitamin C retention time in the bloodstream. With simple graphs and uncomplicated language, the authors illustrate 1) how high oral
doses of vitamin C yield higher blood levels of the vitamin, and 2) how dividing the oral doses maintains those higher levels. Although initially seeming almost too obvious to mention, these are not self-evident concepts. Government-based intake standards such as the RDA hinge on
ignoring them.

Hickey and Roberts zero in on this serious public health error. Their critical analysis of research studies purporting to justify a mere 100 or 200 mg/day ascorbate dose is worthy of Linus Pauling himself. Dr. Roberts says: "Stressed and even mildly ill people can tolerate 1,000 times more vitamin C, implying a change in biochemistry that was ignored in creating the
RDA. The RDA concept does not differentiate between short and long- term effects of deprivation.

The possibility that sub-clinical scurvy causes chronic disease has enormous implications for health. In setting the RDA, unsubstantiated risks of taking too much vitamin C have been accorded great importance, whereas the risks of not taking enough have been ignored. Real scientists understand that 'no scientific proof' is a fancy way of saying 'we don’t like this idea.' Furthermore, there is no clear mechanism for the RDA to be modified when new scientific evidence emerges."

Ascorbate: The Science of Vitamin C is a compellingly written, fast-paced inspection of belief-based bias that permeates the scientific method. It is not a tirade; Hickey and Roberts simply tell it the way it is. They are well qualified to do so. Steve Hickey has a PhD in Medical Biophysics from the University of Manchester, and spent about ten years in research at the
Manchester Medical School and associated hospitals. Interestingly, he had initially trained as a biologist specializing in pharmacology, later switching to biomechanics and medical physics. In addition to degrees in physiology and computer science, Hilary Roberts' University of Manchester PhD was on the effects of early life malnutrition. She spent ten years in research
and teaching at the university.

When asked how he and his coauthor came to write the book, Dr. Hickey said: "Since Linus Pauling's death, there seemed to be a great deal of misinformation. The NIH had performed some questionable experiments and were making the apparently ridiculous statement that blood plasma and tissues became saturated with low doses of vitamin C. There was no mainstream research on high doses and the establishment was making wild extrapolations from their low dose data. We could not see how a clinical trial with 200 mg of vitamin C, for example, could be used to suggest that higher doses were not effective. The work of physicians like Robert Cathcart, Archie Kalokerinos and Abram Hoffer intrigued us. The reported effects, especially of intravenous vitamin C, were astounding. It was difficult to find any reason to explain the lack of scientific follow-up. We had friends and relatives that were sick or dying from diseases that
high dose vitamin C was claimed to cure. Eventually we felt we had no choice but to write the book."

Dr. Roberts adds: "Most RDA standards are based on data which was not measured in actual experiments on real people. Even the small amount of data from the 19–30 year old subjects, who were measured, is based on neutrophils, a white blood cell type that is known to have unusual vitamin C biochemistry, along with an exceptional ability to pump the vitamin into
itself. Neutrophils have ascorbate levels from 25-60 times that of the surrounding plasma. This cell type is not a reliable model for the whole body."

Additional topics discussed in Ascorbate: The Science of Vitamin C include infectious disease, oxidation and illness, the safety of vitamin C, and a presentation of the authors' dynamic flow model of continual vitamin C-mediated tissue reduction. The book contains substantial sections
devoted to cardiovascular disease, with the welcome inclusion of an efficient discussion of the roles of vitamin E and lysine. Two excellent chapters on cancer take the starch right out of the Mayo Clinic "refutations" of the Pauling/Cameron vitamin C studies. The authors state that Dr.
Charles "Moertel's switch to oral does would clearly have biased the results" even though Pauling "stated clearly that intravenous doses are more effective than oral doses and explained the reasons for the difference."

Ascorbate: The Science of Vitamin C contains 575 references, and especially good ones. Though not alphabetized, all are keyed to the text with numbered footnotes. For a book this important, the index could be and should be more detailed. A glossary is included for the general reader.
All will enjoy the well-selected epigrams that form the chapter lead-in quotes.

The authors expert command of their topic has enabled them to successfully encompass an enormous, and enormously important, subject. To make a 216-page book this comprehensive, and also so exceptionally comprehensible as well, is no small achievement.

I wish I'd had a book of this caliber back in the 1970's when my kids were infants. I raised my children all the way into college without a single dose of any antiviral, antihistamine, or antibiotic. What they did get were megadoses of vitamin C. We, like so many other parents, learned the
principles of vitamin C therapy (quantity, frequency, and duration) at our kids' bedsides at three in the morning. Now, the pioneering work of megascorbate orthomolecular physicians has been concisely summarized and very skillfully explained in Ascorbate: The Science of Vitamin C. It is a thorough, up to date and very readable analysis of what, to some, may still appear to be a controversial topic.

Those who use it know that taking enough C results in three C's: patient comfort, low cost, and parental control. Without necessitating the use of invasive technology, nor the trauma of hospitalization, parents can regain confidence and mastery over illness to a degree that they might never have thought possible. For this reason, vitamin C therapy will, at least in
some quarters, continue be decried and denounced as irresponsible. It takes some real ego strength for a parent to stand firm and say, "This is what I am going to do: I am going to follow the Klenner/Pauling/Cathcart vitamin C protocol." Hickey and Roberts' review of vitamin C research is a solid buttress that makes such a stance possible. No bias or belief system
can withstand their first-rate presentation of the safety and effectiveness of megadoses of ascorbate.

Hickey S and Roberts H. Ascorbate: The science of vitamin C. 2004. ISBN 1-4116-0724-4. Morrisville, NC: Lulu.com. www.lulu.com/ascorbate NEW REVIEW of DOCTOR YOURSELF: Natural Healing that Works "Take Charge of Your Own Health"

Review by Beatrice Trum Hunter, in the Townsend Letter for Doctors and Patients

Several recently published books deal with subjects that emphasize the importance of an individual taking charge of health practices and decisions. . . The illnesses and health problems discussed in Doctor Yourself: Natural Healing that Works are presented in alphabetical order,
and include acid reflux, allergies, hemorrhoids, sleep disorders, and vaccinations, among many others. According to Andrew Saul, many diseases can be treated with safe, inexpensive, and drugless approaches. He writes conversationally, interspersing protocols with personal
experiences and case stories. Take psoriasis, an intractable condition. Try a complete change of diet, with fresh foods, vegetable juices, lecithin, and vitamins including extra vitamin D, instead of the palliative ointments and lotions. For additional information on the scientific studies supporting the protocols. Dr. Saul refers readers to DoctorYourself.com website with
more than 4000 references.

Doctor Yourself: Natural Healing that Works, by Andrew, Saul, PhD.

(oversized quality paperback, 241 pages, bibliography, index, 2003) [from the Townsend Letter for Doctors and Patients, #253-254, May 2004, p 132. http://www.townsendletter.com/ / Telephone (360)385-6021.] Editor's Note: This particular review was a special treat for me. Beatrice Trum Hunter's NATURAL FOODS COOKBOOK (New York: Pyramid, 1961) was one of the very first health books I read. (It is reviewed at http://www.hoboes.com/html/Diner/revue/naturalfoods.shtml) I was therefore most honored to have made her list of recommended books. Incidentally, the Townsend Letter also very favorably reviewed Doctor Yourself in the Aug-Sept 2004 issue. The review is posted at
http://www.doctoryourself.com/townsend.html . Additional reviews of my book are posted at http://www.doctoryourself.com/saulbooks.html/

TO ORDER AN AUTOGRAPHED COPY of DOCTOR YOURSELF:
Natural Healing that Works, please go to http://www.doctoryourself.com/order.html/

FREE ANTIVIRUS SOFTWARE
There is no longer any excuse to not have the latest and most recent, and
I mean this morning's, antivirus protection. With AVG Free Edition
Antivirus software, such protection is free and updates are, too. I have
used this excellent, downloadable, and totally free of charge program for
years:
http://free.grisoft.com/freeweb.php/doc/2/
(You can also go to http://www.grisoft.com )

FIRM FLUORIDE FACTS
Please especially note the sources of these statements.
"THERE IS NO EVIDENCE THAT FLUORIDE IS AN ESSENTIAL
NUTRIENT FOR HUMANS." (Physicians' Desk Reference)
http://www.pdrhealth.com/drug_info/nmdrugprofiles/nutsupdrugs/flu_0109.shtml

FLUORIDE IS NOT APPROVED BY THE U.S. FOOD AND DRUG ADMINISTRATION http://www.cm-life.com/vnews/display.v/ART/2004/12/06/41b3e6ab68a3c

("CITY REMOVES FLUORIDE FROM WATER. The City of Mount Pleasant (Michigan) followed the will of its resident-voters and began removing fluoride from its water supply. . . (City) ordinance states anything added to the city water must be approved by the Food and Drug
Administration, and fluoride is not.")

FLUORIDE DOES NOT WORK
California is 28% fluoridated; Hawaii is 9% fluoridated. These states are tied for the lowest rate of tooth loss in the USA. On the other hand, Kentucky is 100% fluoridated and has the highest toothless population of older adults.

(http://www.latimes.com/features/health/medicine/la-me-health2jan02,1,2990789.story?coll=la-health-medicine)

CORRECTION: My review of Pottenger's Cats, in the December, 2004 Newsletter (posted at http://www.doctoryourself.com/news/v5n1.txt ) omitted rightful mention of the Selene River Press (http://www.seleneriverpress.com/), publisher and distributor of health books.
They kindly provided me with the review copy of Pottenger's Cats.

VITAMIN E WITCH HUNT
by Michael Fumento
http://www.fumento.com/nutr/vitamine.html
Less than two months ago I debunked a report in the Lancet medical journal claiming antioxidants slightly increase your chance of dying, rather than reducing it as most researchers believe. Now I'm writing about a report that says the same thing about a specific antioxidant, vitamin E. Why are these pills being persecuted? Among the similarities of the earlier report and this one, authored by researchers at the Johns Hopkins School of Public Health, is that the mainstream media accepted both without question. Both times the researchers smugly declared their work to be the final word on the subject, though both reports were, as the vitamin E one
admitted, 'a qualitative departure from previous findings.'

Since a good scientist knows no single report ever proves anything, we know these weren't good scientists. In fact, they have less in common with Johns Hopkins than Matthew Hopkins - England's infamous 'Witch-finder General.'
Consider the vitamin E paper, published in The Annals of Internal Medicine (full citation at http://www.doctoryourself.com/safety.html ). It analyzed 19 clinical trials between 1993 and 2004, involving 136,000 people in all. These were combined into what's called a 'meta-analysis,'
which showed no overall increase in deaths. But at high levels, defined as above 400 international units (IUs) per day, the researchers insisted 'vitamin E supplements may increase (deaths) and should be avoided.'
A glaring problem with the report is that there have been far more than 19 vitamin E trials since 1993, and one way the pack was whittled down was by excluding all studies reporting fewer than 10 deaths. The witch-hunters weren't about to interrogate witnesses who might keep the accused from a visit to the gallows.
Also, if 'more is worse,' why did the two studies that used the highest dose, 2,000 IUs per day, indicate fewer deaths among vitamin E users? Another problem with declaring this report to be the final word on vitamin E is that while clinical trials are important, epidemiological studies cannot be ignored. Yet ignored they were.

Thus there was no reference to the 1996 one from the National Institute of Aging that followed 11,000 elderly persons for seven years and found that the death rate for vitamin E users was a third that of non-users. Adding another antioxidant, vitamin C, cut fatalities even more.

A 1993 Harvard study of 40,000 male health professionals found those who took at least 100 IUs daily for two years had a third fewer cases of heart disease than those receiving no vitamin E supplements.
A Harvard study of 87,000 nurses that year found an even greater reduction in heart disease when comparing women who took the highest amount of vitamin E vs. those taking the lowest amount. Does this have you running in terror at the sight of a vitamin E capsule?

But what's with the supplement witch-hunt? Why the reports of vitamin E flying on broomsticks, and beta carotene casting hexes? "Unfortunately, there are some doctors who are biased against dietary supplements," says John Hathcock, vice president of Scientific & International Affairs at the D.C.-based Council for Responsible Nutrition. To an extent, this is understandable. For one, some supplements are worthless while a few have proved harmful. But you just can't lump 'eye of newt' in together with vitamin E or other antioxidants.
Mainstream medicine is also biased toward that which has formal FDA approval. You know, like Vioxx. And never mind the many supplements such as iron and iodine that have tacit FDA support but no formal approval.

Some doctors also fret that people will try to substitute supplements for good eating habits. 'We don't think that people need to take vitamin E supplements, that they get enough from the diet,' said the lead vitamin E prosecutor, associate professor Edgar Miller.
Yet the average American gets only about 10 IU daily. With some studies showing 2,000 IUs to be beneficial, dietary intake leaves us a bit shy of the mark. Anyway, those taking vitamins and other supplements also have the best diets.
The final explanation for vitamin-pill persecution is that medical journals are becoming increasingly sensationalist. Publishing articles contrary to popular wisdom is a cheap and easy way to get headlines. But there's no excuse for throwing a noose around the neck of good
science and healthful products.
[Reprinted with the kind permission of the author. Michael Fumento http://www.fumento.com/) is a senior fellow at Hudson Institute, syndicated columnist with Scripps Howard News Service and author of BioEvolution: How Biotechnology is Changing our World.]

The GERSON THERAPY MOVIE IS NOW ONLINE!
If you've been wanting to watch THE GERSON MIRACLE ever since I reviewed it the July 20 Doctor Yourself Newsletter (http://www.doctoryourself.com/gersontherapy2.html or http://www.doctoryourself.com/news/v4n16.txt), you are in luck. The entire movie, or any specific chapter you like, can now be viewed FREE OF CHARGE at www.gersonmiracle.org/movie.html . Grab some unsalted popcorn and pull up a chair.

BOOK REVIEW:
FAST FOOD NATION: The Dark Side of the All-American Meal, by Eric
Schlosser.

Boston : Houghton Mifflin, 2001. ISBN: 0395977894
Why, why, why are so many, many, many people so sick, sick, sick? The main reason is staring right back at them from their dinner. It's the junk food, people. An ever-increasing proportion of our food is fast food. "In 1970, Americans spent about $6 billion on fast food; in 2000, they spent more than $110 billion," writes Eric Schlosser in his book Fast Food Nation. "They spend more on fast food than on movies, books, magazines, newspapers, videos, and recorded music - combined. . . On any given day in the United States, about one-quarter of the adult population visits a fast food restaurant." (p 3)

What does this mean to our health? Everything. Fast food is a high- additive, high-fat, high-meat, high-sugar, and high-salt diet. And what's just as bad, it's a low-fiber, low vitamin, low mineral diet to boot. Fast food is exactly the wrong way to eat.

And we are teaching our kids just how to do it . . .wrong. Chapter 2 discusses how the fast-food industry sells to kids, especially in schools. This is the last thing we need; a typical teenage boy already drinks 20 oz of soda a day. Indoctrination starts early: page 30 of Fast Food Nation shows a superb photo of Ronald McDonald speaking to a large room full of enraptured elementary schoolchildren. How can this be?
Because the cafeterias in so many of our school districts are for sale for the right price. The actual franchise income that any school district may get pales when compared to what fast food industry takes in. After all, says Schlosser, "A medium Coke that sells for $1.29 contains roughly 9 cents' worth of syrup."

Adults are to blame. We, not our kids, are the ones who allowed fast food in our schools. We are the ones who let Harlem Memorial Hospital contain its very own McDonald's. It is our money that enables McDonald's to open FIVE new restaurants every DAY. It is our U.S. Federal Communications Commission and our U.S. Federal Trade Commission that permit every American child to watch 10,000 television food ads every year. Are these ads for carrots? Not according to Yale professor Kelly Brownell, PhD., who says that 95% of TV food commercials promote candy, soft drinks and fast food.

Fast Food Nation is much more than a history of soda pop and the flipped burger. In Chapter 3, Schlosser takes us "Behind the Counter" to examine labor issues in the fast food biz. "No other industry in the United States has a workforce so dominated by adolescents," he writes. And teenagers work hard and they work cheap. Too cheap. "Increasing the federal minimum wage by a dollar (an hour) would add about two cents to the cost of a fast food hamburger." Fast Food Nations also explores "Why the Fries Taste Good" in Chapter 5, as well as the very real dangers for those who work at meat packing factories.

Your making a point to read the exceptionally well-written Fast Food Nation would be the perfect New Year's resolution. Here is some video encouragement to help you on your way as you change your lifestyle and fight to eat right:

DIET WARS
"Nobody ever got rich marketing self-control." That is my favorite quote from "Diet Wars," a recent PBS' Frontline presentation. If you missed this truly excellent program, you can still watch it online, for free, at
http://www.pbs.org/wgbh/pages/frontline/shows/diet/view/

Privacy Statement:
We do not sell, and we do not share, our mailing list or your email address with anyone. We never send out advertisements of any kind. You may notice that there is no advertising at http://doctoryourself.com and no advertising in this newsletter. We have no financial connection with the supplement industry. We do not sell vitamins or other health products, except for Dr. Saul's books, which help fund these free public services.

AN IMPORTANT NOTE: This newsletter is not in any way offered as prescription, diagnosis nor treatment for any disease, illness, infirmity or physical condition. Any form of self-treatment or alternative health program
necessarily must involve an individual's acceptance of some risk, and no one should assume otherwise. Persons needing medical care should obtain it from a physician. Consult your doctor before making any health decision.

"DOCTOR YOURSELF" "DoctorYourself.com" and "Doctor Yourself Newsletter" are service marks of Andrew W. Saul. All rights reserved.
Copyright c 2005 and prior years Andrew W. Saul drsaul@doctoryourself.com . Permission to reproduce single copies of this newsletter FOR NON-COMMERCIAL, PERSONAL USE ONLY is hereby granted providing no alteration of content is made and authorship credit is
given.

Tuesday, March 4, 2008

HIGH DOSES OF INTRAVENOUS VITAMIN C FIGHT CANCER

Kathleen Doheny, The New York Times, Tues, Sept.13, 2005
"High doses of vitamin C administered intravenously can fight cancer -- at least in the laboratory, researchers report.

"(The study) examined the body's absorption of the nutrient and found that while oral intake does reach a saturation point, when you give doses intravenously they go through the roof in the blood and then they are cleared, said lead researcher Dr. Mark Levine (chief of the molecular and clinical nutrition section and senior staff physician, National Institute of Diabetes & Digestive & Kidney Diseases). According to Levine, a 10 gram dose (10,000 milligrams) of vitamin C given intravenously produces bloodstream concentrations more than 25-fold higher than concentrations achieved from the same oral dose.

"Some antibiotics are poorly absorbed when given orally but fight infections effectively when given intravenously, and Levine and his team thought that might be the case with vitamin C and cancer. Working with cell lines in the laboratory, they used high doses of vitamin C that could only be achieved by IV administration.

At the highest concentration of ascorbic acid, if given intravenously, they don't touch normal cells and they kill lots of cancer cells. We don't know why, Levine said."

(Editor’s note: Yes, this is certainly good news, although it is not really "news" to most Doctor Yourself Newsletter readers. It is rather an official confirmation, one that has, finally, gotten the attention of the media. Even FOX news picked it up. As Gomer Pyle said, "Goll-y!")

WHY THE DELAY?
Commentary by Bill Sardi
"With a growing body of evidence mounting, National Institutes of Health (NIH) researchers recently conceded that intravenous vitamin C may be an effective treatment for cancer. Last year the same researchers reported a similar study but the news media failed to publish it.
"The latest study, published in the Proceedings of the National Academy of Sciences, confirms the work of Nobel-Prize winner Linus Pauling who conducted cancer research in the 1970s with vitamin C. Dr. Pauling's studies were discredited at the time by poorly conducted research studies at the Mayo Clinic.

"NIH researchers made no mention of their earlier study in 2004 which showed that oral-dose vitamin C can achieve three times greater blood concentration than previously thought possible, a fact which negates the current Recommended Dietary Allowance for vitamin C. NIH researchers refuse to issue a retraction of their earlier flawed research which mistakenly claimed humans cannot benefit from high-dose oral vitamin C supplements."

More at http://www.knowledgeofhealth.com/
Also see: http://www.newmediaexplorer.org/sepp/2005/09/13/cancer_intravenous_vitamin_c_effective_treatment.htm
Full citation:
Qi Chen, Michael Graham Espey , Murali C. Krishna, James B. Mitchell, Christopher P. Corpe, Garry R. Buettner, Emily Shacter, and Mark Levine. Pharmacologic ascorbic acid concentrations selectively kill cancer cells: Action as a pro-drug to deliver hydrogen peroxide to tissues. Proc. Natl. Acad. Sci. USA, 10.1073/pnas.0506390102
"Extracellular but not intracellular ascorbate mediated cell death, which occurred by apoptosis and pyknosis/necrosis . . . (T)hese data indicate that ascorbate at concentrations achieved only by i.v. administration may be a pro-drug for formation of H2O2, and that blood can be a delivery system of the pro-drug to tissues. These findings give plausibility to i.v. ascorbic acid in cancer treatment..."
This News release was provided by DOCTOR YOURSELF News (Vol. 5 , No. 13 for October, 2005)

Friday, February 29, 2008

HIGH DOSES OF INTRAVENOUS VITAMIN C FIGHT CANCER

Kathleen Doheny, The New York Times, Tues, Sept.13, 2005
"High doses of vitamin C administered intravenously can fight cancer -- at least in the laboratory, researchers report.

"(The study) examined the body's absorption of the nutrient and found that while oral intake does reach a saturation point, when you give doses intravenously they go through the roof in the blood and then they are cleared, said lead researcher Dr. Mark Levine (chief of the molecular and clinical nutrition section and senior staff physician, National Institute of Diabetes & Digestive & Kidney Diseases). According to Levine, a 10 gram dose (10,000 milligrams) of vitamin C given intravenously produces bloodstream concentrations more than 25-fold higher than concentrations achieved from the same oral dose.

"Some antibiotics are poorly absorbed when given orally but fight infections effectively when given intravenously, and Levine and his team thought that might be the case with vitamin C and cancer. Working with cell lines in the laboratory, they used high doses of vitamin C that could only be achieved by IV administration.

At the highest concentration of ascorbic acid, if given intravenously, they don't touch normal cells and they kill lots of cancer cells. We don't know why, Levine said."

(Editor’s note: Yes, this is certainly good news, although it is not really "news" to most Doctor Yourself Newsletter readers. It is rather an official confirmation, one that has, finally, gotten the attention of the media. Even FOX news picked it up. As Gomer Pyle said, "Goll-y!")

WHY THE DELAY?
Commentary by Bill Sardi
"With a growing body of evidence mounting, National Institutes of Health (NIH) researchers recently conceded that intravenous vitamin C may be an effective treatment for cancer. Last year the same researchers reported a similar study but the news media failed to publish it.
"The latest study, published in the Proceedings of the National Academy of Sciences, confirms the work of Nobel-Prize winner Linus Pauling who conducted cancer research in the 1970s with vitamin C. Dr. Pauling's studies were discredited at the time by poorly conducted research studies at the Mayo Clinic.

"NIH researchers made no mention of their earlier study in 2004 which showed that oral-dose vitamin C can achieve three times greater blood concentration than previously thought possible, a fact which negates the current Recommended Dietary Allowance for vitamin C. NIH researchers refuse to issue a retraction of their earlier flawed research which mistakenly claimed humans cannot benefit from high-dose oral vitamin C supplements."

More at http://www.knowledgeofhealth.com/
Also see: http://www.newmediaexplorer.org/sepp/2005/09/13/cancer_intravenous_vitamin_c_effective_treatment.htm
Full citation:
Qi Chen, Michael Graham Espey , Murali C. Krishna, James B. Mitchell, Christopher P. Corpe, Garry R. Buettner, Emily Shacter, and Mark Levine. Pharmacologic ascorbic acid concentrations selectively kill cancer cells: Action as a pro-drug to deliver hydrogen peroxide to tissues. Proc. Natl. Acad. Sci. USA, 10.1073/pnas.0506390102

"Extracellular but not intracellular ascorbate mediated cell death, which occurred by apoptosis and pyknosis/necrosis . . . (T)hese data indicate that ascorbate at concentrations achieved only by i.v. administration may be a pro-drug for formation of H2O2, and that blood can be a delivery system of the pro-drug to tissues. These findings give plausibility to i.v. ascorbic acid in cancer treatment..."

This News release was provided by DOCTOR YOURSELF News (Vol. 5 , No. 13 for October, 2005)