Stress, Anxiety Worsen Response to Allergens

(HealthDay News) -- Even a little stress and anxiety can greatly worsen and extend a person's reaction to common allergens, a new study says.

The finding, to be presented Thursday at the American Psychological Association annual meeting, in Boston, are important, as allergies are the fifth-most-common chronic disease in the United States. The researchers estimated that Americans pay more than $3.4 billion for allergy medications and allergy-related doctor visits annually, and lose about 3.5 million work days a year because of them.

"Allergies are not minor problems," researcher Jan Kiecolt-Glaser, a professor of psychology and psychiatry at Ohio State, said in a news release issued by the university. "A huge number of people suffer from allergies and, while hay fever, for example, is generally not life-threatening, allergy sufferers often also have asthma, which can be deadly."

The study looked at 28 volunteers with a history of hay fever and seasonal allergies. Researchers gave standard allergy prick tests to the volunteers, then measured the raised "wheals" that formed on the arms of the participants before and after they were subjected to stressful situations, such as given a speech and answering a series of math questions. They were tested again the next day as well. Read more...

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Five healthy practices dramatically reduce stroke risk in large study population

Few conditions are more devastating than stroke, yet an article published ahead of print on August 12, 2008 in the American Heart Association journal Circulation reports that just five healthy lifestyle factors may confer significant protection against the event. Read more

Why stress is aging?

Readers of Life Extension Update may recall the November 29, 2004 issue which described an association between emotional stress and shortened telomeres, a marker of cellular aging. Now, in research published in the May, 2008 issue of Brain, Behavior and Immunity, a team at the University of California, Los Angeles report that they may have discovered why.

Telomeres are caps at the ends of chromosomes (the genetic material of the cell) that contribute to their stability. Each time a cell divides, telomeres lose length. Telomeres also lose length in response to chronic stress. Shortened telomeres in white blood cells known as lymphocytes have been associated with HIV, osteoporosis, heart disease and aging. An enzyme within the cell known as telomerase helps prevent telomere shortening and maintains the cells' ability to continue dividing.

For the current investigation, UCLA David Geffen School of Medicine professor of pathology and laboratory medicine Rita Effros and colleagues studied lymphocytes from healthy male and female donors between the ages of 25 and 55. The cells were treated with varying concentrations of cortisol, the hormone released by the body when under stress, or with DMSO (as a control). Continue Reading

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