Thursday, November 11, 2010

Calorie restriction keeps its followers young at heart

In research published in the January 17 2006 issue of the Journal of the American College of Cardiology, Luigi Fontana MD, PhD, and colleagues at Washington University School of Medicine in St. Louis, Missouri reported that individuals who have adopted a calorie restricted yet nutritionally balanced diet have the heart function of people much younger. "This is the first study to demonstrate that long-term calorie restriction with optimal nutrition has cardiac-specific effects that ameliorate age-associated declines in heart function," Dr Fontana announced.

The team studied 25 members of the Caloric Restriction Optimal Nutrition Society, who consume approximately 1,400 to 2,000 calories per day, which is 10 to 25 percent fewer calories than most Americans, while maintaining nutritionally adequate diets. Diastolic function of the heart, which is the ability of the organ to relax between beats and which, unlike systolic function, declines with age, was evaluated via ultrasound. Blood samples were evaluated for C-reactive protein, tumor necrosis factor-alpha, and transforming growth factor-beta 1, which are involved with inflammation. Read more...

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