For their research, Texas AgriLife Research scientist Dr Nancy Turner and her colleagues gave 40 rats diets supplemented with or without quercetin. During the second and fourth weeks of the experiment, the animals were injected with azoxymethane, a carcinogen used to induce colon cancer in rodents, or with saline as a control. Four weeks following the last injection, the rats’ colons were examined.
Animals that received quercetin had fewer high multiplicity aberrant crypt foci, a marker or predictor of tumor formation that had previously been shown to be reduced by quercetin. "Early lesions in a colon are some of the first true changes in the colon that can be observed visually," Dr Turner remarked. "This is not just something you see in our animal model. You see it in human patients as well." Continue Reading
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