Thursday, October 30, 2008

Berries protect against carcinogen-induced gene changes

The August 1, 2008 issue of the journal Cancer Research published the finding of researchers at Ohio State University that consuming black raspberries can prevent some of the genetic changes that result from carcinogen exposure, thereby reducing the risk of cancer.

Professor of pathology and human nutrition Gary D. Stoner and his associates fed rats a normal diet or a diet that contained 5 percent freeze-dried black-raspberry powder for three weeks. “Freeze drying the berries concentrates these elements about ten times, giving us a power pack of chemoprevention agents that can influence the different signaling pathways that are deregulated in cancer,” Dr Stoner noted.
During the third week of the diet, half of the animals were injected with the carcinogen N-nitrosomethylbenzylamine, and genetic changes in the esophagus were measured. Among rats that received the carcinogen, 2,261 of 41,000 genes examined showed a 50 percent or more change in activity, yet in animals that received berry powder, 462 of these altered genes demonstrated near-normal activity. Continue Reading

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