In the July 28, 2008 issue of the American Medical Association journal Archives of Internal Medicine, researchers at Addenbrooke’s Hospital and the University of Cambridge in England report an association between higher plasma vitamin C levels in middle-aged adults and a lower risk of developing type 2 diabetes.The study included 21,831 healthy, nondiabetic participants in the European Prospective Investigation of Cancer-Norfolk study, which was created to examine the association between diet and cancer. Vitamin C levels were measured in plasma, and food frequency questionnaires were administered upon enrollment between 1993 and 1997. Over a twelve year follow-up period, 423 men and 312 women developed diabetes.
Analysis of the data revealed a strong protective effect of high vitamin C levels against diabetes. Participants in the top 20 percent of plasma vitamin C had a 62 percent lower adjusted risk of developing diabetes compared with those in the lowest fifth. Fruit and vegetable intake also emerged as protective. Those whose intake was in the top fifth had a 22 percent lower diabetes risk than subjects whose intake was lowest. Continue Reading
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